符合线路SPECT-^(18)FDG显像诊断肺癌的研究  

A Study of ^(18)FDG imaging with coincidence SPECT for the diagnosis of lung cancer

作　　者：苗积生[1] 王火强[1] 潘惠忠[1] 刘进军[1] 吴吉勇[1] 沈毅[1] 

机构地区：[1]上海市肺科医院,上海200433

出　　处：《核技术》2000年第5期305-307,共3页Nuclear Techniques

摘　　要：用双探头ＥＣＴ进行^（１８）ＦＤＧ符合线路显像，探讨对肺癌的诊断价值。 ３９例未确诊的肺部病变患者，禁食４ｈ静脉注入３７－１１１ＭＢｑ^（１８）ＦＤＧ。静休１－２ｈ在胸部行断层显像，用叠代法重建。检测病灶区与对侧对照区核素的浓聚比值，超过１．３为显像阳性。根据显像结果对肺癌诊断的灵敏度是９３％（２５／２７），特异性８３％（１０／１２），符合率９０％（３５／３９）。本显像技术对肺癌诊断有较好的应用价值。SPECT coincidence imaging was performed on a dual-head gamma camera (DST-XLi, SMV) to allow the detection of 511keV gamma emission of ^(18)FDG positron radionuclides. ^(18)FDG was provided by Shanghai Institute of Nuclear Research. All the patients with lung lesions on X-ray film have not yet confirmed in diagnosis underwent ^(18)FDG imaging. Patients fasted 4 hours before administration of ^(18)FDG and kept rest from 1-2 hours after intravenous administration of 37-111MBq ^(18)FDG. Images were reconstructed by lterative reconstruction. Draw ROI on lesion area (L) and control area (C). The L/C ratio larger than 1.3, it was considered positive. Of total 39 cases, the sensitivity, specificity and accuracy was 93%(25/27), 83%(10/12) and was 90%(35/39) respectively, for the diagnosis of lung cancer. Therefore coincidence imaging of ^(18)FDG-SPECT is a suitable and reliable new technology for the diagnosis of lung cancer.

关 键 词：SPECT 肺癌 诊断 氧-18 同位素诊断 

分 类 号：R734.204[医药卫生—肿瘤] R730.44[医药卫生—临床医学]