原发性肝脏神经内分泌癌3例报道  

Three Cases Reports of Primary Hepatic Neuroendocrine Carcinoma

作　　者：田义阳[1] 陈哲宇[1] 

机构地区：[1]四川大学华西医院肝胆胰外科,四川成都610041

出　　处：《中国普外基础与临床杂志》2013年第5期529-531,共3页Chinese Journal of Bases and Clinics In General Surgery

摘　　要：目的总结原发性肝脏神经内分泌癌的诊治经验。方法回顾性分析我院2010年6月至2011年6月1年间约1000例肝切除病例中发现的3例原发性肝脏神经内分泌癌的临床病理资料。结果 3例病例术前结合临床资料难以诊断原发性神经内分泌癌,治疗方式均采用手术切除,经病理检查及免疫组织化学报告3例均属于低分化神经内分泌癌,术后均使用奥曲肽辅助治疗,患者康复出院,随访1年肿瘤无明显复发。目前3例患者仍在随访中。结论原发性肝脏神经内分泌癌的术前诊断较为困难,治疗和疗效的评估目前在探索中。Objective To summarize the diagnosis and treatment for primary hepatic neuroendocrine carcinoma.Methods The clinicopathologic data of three patients with primary hepatic neuroendocrine carcinoma from June 2010 to June 2011 in this hospital were analyzed retrospectively.Results Three cases were difficult to diagnose primary hepatic neuroendocrine carcinoma before operation.All the treatments were resection.Three patients were diagnosed as neuroendocrine carcinoma by pathology and immunohistochemistry after operation.All of them were treated by octreotide after operation and discharged from hospital successfully.There was no relapse one year later.At present,3 patients were still continue to follow-up.Conclusions The diagnosis of primary hepatic neuroendocrine carcinoma is very difficult before operation,the assessment of treatment and curative effect is exploring.

关 键 词：原发性肝脏神经内分泌癌 诊断 治疗 

分 类 号：R735.7[医药卫生—肿瘤]