羊膜移植与自体角膜缘球结膜移植治疗翼状胬肉的疗效分析  

Amniotic membrane transplantation and limbal conjunctival transplantation in treatment of pterygium

作　　者：蔡丽萍[1] 雷小龙[1] 

机构地区：[1]甘肃省天水市第一人民医院眼科,天水741000

出　　处：《中国中医眼科杂志》2013年第2期114-116,共3页China Journal of Chinese Ophthalmology

摘　　要：目的探讨羊膜移植与自体角膜缘球结膜移植联合胬肉切除治疗翼状胬肉的疗效。方法初发性翼状胬肉285例(308只眼),其中164例(176只眼)行新鲜羊膜移植联合胬肉切除术,121例(132只眼)行自体角膜缘球结膜移植联合胬肉切除术,随访2～5年,平均3.4年。结果新鲜羊膜移植联合胬肉切除术组164例(176只眼)中有25只眼复发,复发率为14.21%,进行期53只眼中有16只眼复发,占复发病例的64.0%,45岁以下有18只眼复发,占复发病例的72.0%。自体角膜缘球结膜移植联合胬肉切除术组121例(132只眼)中有19只眼复发,复发率为14.39%,其中进行期44只眼中有10只眼复发,占复发病例的52.63%,45岁以下有12只眼复发,占复发病例的63.16%。2组复发率比较,差异无统计学意义(c2=2.07,P>0.05)。结论 2种手术后复发率较单纯切除明显下降,但仍有一定程度的复发,进行期病例的复发率高,中年人较老年人术后复发率高。OBJECTIVE To observe the therapeutic effects in treatment of amniotic membrane transplantation and limbal bulbar conjunctiva transplantation. METHODS There were 285 patients （302 eyes） with initial pterygium, excision of pterygium with fresh amniotic membrane transplantation surgery （ 164 cases and 176 eyes）, escision of pterygium with limbal bulbar conjunctiva transplantation （ 121 cases and 132 eyes）. All patients had been followed up for 2-5 years. RESULTS The recurrence rate was 14.21% （25 nut nf 17t^amniotic membrane transplantation, the recurrence rate was 64.0%（16 out of 53 eyes） for period pterygium, therecurrence rate was 72.0% （18 eyes） under 45 years old; The recurrence rate was 14.39% （19 out of 132 eyes） in limbal bulbar conjunctiva transplantation, the recurrence rate was 52.63% （10 out of 44 eyes） for period pterygium, the recurrence rate was 63.16% （12 eyes） under 45 years old. CONCLUSIONS Both methods could help reduce the recurrence rate, but there was still a certain degree of relapse. Recurrence rate for stage cases was high. The middle- aged got higher recurrence rate than the aged.

关 键 词：翼状胬肉 复发 移植 新鲜羊膜 自体角膜缘球结膜 

分 类 号：R777.33[医药卫生—眼科]