局部晚期直肠癌新辅助治疗疗效的影像学评估  

Imaging assessment of therapeutic efficacy of neoadjuvant therapy for locally advanced rectal cancer

作　　者：熊伟[1] 李云峰[1] 李支尧[2] 高德培[3] 余昆[1] 夏翠锋[1] 

机构地区：[1]云南省肿瘤医院昆明医科、大学第三附属医院大肠癌临床诊疗中心,650032 [2]云南省肿瘤医院超声科,650032 [3]云南省肿瘤医院影像科,650032

出　　处：《中华消化外科杂志》2013年第6期447-451,共5页Chinese Journal of Digestive Surgery

基　　金：云南省教育厅科学研究基金（06y120c）

摘　　要：直肠癌的治疗规范目前仍没统一，尤其对于局部晚期直肠癌（T3、T4期）患者，治疗方法争议较大，目前较为一致的意见是采取多学科综合治疗。为此，对局部晚期直肠癌的术前准确诊断、分期就显得尤为重要，这决定了其治疗方法的应用并对治疗效果产生重要影响。目前，经直肠腔内超声（TRUS）、多层螺旋CT、MRI等影像学检查在局部晚期直肠癌的术前诊断、分期的应用中占有较为重要的地位，但国内外在不同影像学对直肠癌评估的研究结果并不一致。本研究回顾性分析2010年10月至2012年10月云南省肿瘤医院收治的30例局部晚期直肠癌患者新辅助治疗前后的影像学资料，得出TRUS、CT、MRI等影像学检查在局部晚期直肠癌综合分期及新辅助治疗疗效评估中有较好的指导应用价值，为进展期直肠癌选择恰当的治疗方案提供更可靠的依据。The standard treatment for colorectal cancer still have not been unified, especially the treatment for patients with locally advanced rectal cancer （T3 or T4 stage） is contro- versial, and multidisciplinary comprehensive treatment is recom- mended by most of the scholars. Precise preoperative diagnosis and staging for locally advanced rectal cancer is very important. Currently, transrectal ultrasound （ TRUS ） , multi-slice spiral computed tomography, magnetic resonance imaging （MRI） are playing important roles in the preoperative diagnosis and staging, while controversies on the efficacies of different imaging diagnosis on the evaluation of rectal cancer exist between domestic and overseas scholars. From October 2010 to October 2012, the imaging data of 30 patients with locally advanced rectal cancerwho were admitted to the Tumor Hospital of Yunnan Province were retrospectively analyzed. The results showed that TRUS, computed tumography and MRI had guidance value in preopera- tive tumor staging and evaluation of neoadjuvant therapy for patients with locally advanced rectal cancer, which provide a more reliable basis for the selection of appropriate treatment programs.

关 键 词：直肠肿瘤 放疗 化疗 影像学检查 疗效 

分 类 号：R735.37[医药卫生—肿瘤]