巨大间质瘤并右侧腹股沟巨大疝的诊断和治疗  

Diagnosis and treatment of huge gastrointestinal stromaltumor combined with large inguinal hernia

作　　者：陈新岐[1] 吕会增[1] 叶小勇[1] 张文海[1] 张帆[1] 张实[1] 

机构地区：[1]广州医学院第五附属医院普通外科,510700

出　　处：《中华消化外科杂志》2013年第6期475-476,共2页Chinese Journal of Digestive Surgery

摘　　要：胃肠道间质瘤（GIST）是一种较常见的以c-kit基因突变为特征的消化道间叶细胞肿瘤，最常发生于胃。结合B超、CT检查和肿瘤标志物CD117检测多可诊断。手术根治性切除是其最有效的治疗手段。靶向药物可延缓肿瘤复发和远处转移患者的疾病进展。目前对于巨大GIST的诊断及手术、药物治疗时机仍存争议。现就一例巨大胃间质瘤合并巨大腹股沟疝展开讨论，以便为临床制订合理的诊断和治疗措施提供参考。Gastrointestinal stromal tumors （ GISTs ） are relatively common mesenchymal tumors of the digestive tract characterized by e-kit mutations and the stomach is the commonly involved site. Clinical and pathological diagnosis of GISTs can be achieved by B sonography, computed tomography and immuno- histochemical detection of marker CD117. Surgical resection of GISTs has been the most effective therapy. Target therapy with tyrosine kinase inhibitors may reduce the development of recur- renee or progression of GISTs. The optimized method of diagnosis and treatment of huge GISTs is still controversial. In this paper, the diagnosis and treatment for huge GIST combined with large right inguinal hernia were discussed.

关 键 词：胃肠道间质肿瘤 腹股沟疝 诊断 治疗 

分 类 号：R735[医药卫生—肿瘤]