不同脉冲时间半导体激光经巩膜睫状体光凝治疗难治性青光眼临床疗效比较  

Comparison of Clinical Efficacy of Transscleral Diode Laser Cyclophotocoagulation （TSCPC） with Different Pulse time for the Treatment of Refractory Glaucoma

作　　者：宋鹤翔[1] 苗林[1] 曹西友[1] 

机构地区：[1]上海市普陀区人民医院,上海200060

出　　处：《医学临床研究》2013年第5期912-914,共3页Journal of Clinical Research

摘　　要：【目的】比较不同脉冲时间半导体激光经巩膜睫状体光凝术治疗难治性青光眼的临床疗效。【方法】将晚期难治性青光眼患者58例60眼随机分成两组，采用810nm半导体激光，分别应用长脉冲时间（4s）和传统标准脉冲时间（2s）行经巩膜睫状体光凝术，观察眼压、并发症，评价治疗效果。【结果】长脉冲时间组（30只眼），眼压由术前（55．29士12．38）mmHg降至（20．21±11．83）mmHg，显效率79％，术后疼痛、前房反应、出血较轻；传统标准脉冲时间组例（30只眼），眼压由术前（54．47±15．14）mmHg降至（19．81±13．29）mmHg，显效率为81％，术后疼痛、前房反应、出血较重。两组术后降低眼压的治疗效果无显著差异（P〉0．05），长脉冲时间组比标准脉冲时间组疼痛及并发症更轻更少（P〈0．05）。【结论】半导体激光经巩膜睫状体光凝术治疗难治性青光眼效果明显，其中采用长脉冲时间（4s）比传统标准脉冲时间（2s）在有效降低眼压的同时并发症更少，更安全，特别对有视力眼临床意义更大。[Objective] To compare the clinical efficacy of transscleral diode laser cyclophotocoagulation （TSCPC） with different pulse time for the treatment of refractory glaucoma. [Methods] A total of 58 patients （60 eyes） with late refractory glaucoma were randomly divided into 2 groups. All patients underwent 810ram TSCPC with long pulse time（4s） and standard pulse time（2s）, respectively. Intraocular pressure（IOP） and the complications were observed, and the efficacy was assessed. [Results]In long pulse time group, IOP decreased from （55.29±12.38）mmHg before operation to （20.21 ±11.83）mmHg after operation, and the effective rate was 79 ± In standard pulse time group, IOP decreased from （54.47 ± 15.14）mmHg before operation to （19.81±13.29）mmHg after treatment, and the effective rate was 81 ~, and had postoperative pain, anterior chamber reaction and severe bleeding. There was no significant difference in the efficacy for decreasing lOP after operation between two groups（ P 〈0.05）. The long pulse time group had less and slighter complications such as pain than standard pulse time group（ P〈0.05）. [Conclusion] TSCPC for the treatment of refractory glaucoma has obvious effect. Compared with TSCPC with standard pulse time（2s）, TSCPC with long pulse time（4s） can equally decrease the IOP, and has less complications and is safer, and is of more significance es- pecially for the eyes with vision.

关 键 词：青光眼 治疗 激光疗法 巩膜 睫状体 

分 类 号：R775[医药卫生—眼科]