常德地区脑卒中后抑郁症调查及相关因素分析  

Survey on Post-stroke Depression in Changde Area and the Correlative Factor Analysis

作　　者：洪云军[1] 徐平[1] 高云春[1] 彭玉[1] 苏化庆[1] 

机构地区：[1]湖南省常德市第一人民医院神经内科,湖南长沙415003

出　　处：《医学临床研究》2013年第5期944-946,共3页Journal of Clinical Research

摘　　要：【目的】调查常德地区脑卒中患者卒中后抑郁症（PSD）的发生率及分析其相关因素，并探讨抑郁对脑卒中患者神经功能康复的影响。【方法】以个人访谈的形式对2011年1月至2011年12月常德地区17家医院卒中登记的468例患者进行问卷调查，记录基本信息（年龄、性别、文化程度），采用汉密尔顿抑郁量表（HRSD-24）评定抑郁严重程度，采用美国国立卫生所卒中量表（NIHSS）评定神经功能缺损程度，根据研究对象年龄、性剐、受教育程度及是否存在抑郁等不同条件进行分组，用SPSS13．0软件包进行数据统计分析。【结果1468例卒中患者中，PSD的发生率为47．9％；男和女PSD发生率比较（44．0％VS53．4％）差异存在统计学意义。按文化程度分组，小学组PSD发生率为58．8％。不同年龄段PSD发生率分别为：〈60岁65．3％、60～69岁48．6％、70～79岁37．9％、≥80岁35．2％。PSD发生率随年龄增高而下降。PSD患者NIHSS评分高于卒中后非抑郁患者（P〈0．05）。【结论】脑卒中患者PSD发生率高，其神经功能缺损程度明显高于卒中后非抑郁患者。重视PSD的治疗有利于其神经功能缺损的康复。[Objective]To investigate the prevalence rate of post-stroke depression（PSD） in Changde area, and to analyze the correlative factors, and to explore the effect of depression on the recovery of nerve function in patients with stroke. [Methods]From Jan. 2011 to Dec. 2011, a questionnaire survey was conducted among 468 patients with stoke registered in multiple hospitals of Changde area via personal interview. The basic information（age, sex and education level） were recorded. Hamilton depression scale（HRSD-24） was used to assess the severity of depression. American national institutes of health stroke scale（NIHSS） was used to assess the degree of neural function defect. According to age, gender, education level, the presence of depression and other different conditions of research subjects, all patients were grouped. SPSS 13.0 software was used for statistical data analysis. [Results]Of 468 patients with stroke, the prevalence rate of PSD was 47.9%. There was significant difference in the prevalence rate of PSD between male patients and female patients（44.0% vs .53.4）. The prevalence rate of PSD in primary school group was 58.8%. The prevalence rate of PSD at different ages（〈60, 60-69, 70-79 and ≥80 years old） were 65.3%, 48.6%, 37. 9% and 35.2%, respectively. The prevalence rale of PSD decreased with the age. NIHSS score of PSD patients was higher than that of stroke patients without depression（ P〈0. 05）. [Conclusion] Stroke patients have high prevalence of PSD. Neurologic impairment of stroke patients is more serious than that of stroke patients without depression. Paying attention to the treatment of PSI） is conducive to the rehabilitation of nerve function defect.

关 键 词：卒中 并发症 抑郁症 流行病学 湖南 

分 类 号：R743.3[医药卫生—神经病学与精神病学]