脑膜瘤瘤周水肿与病理学分型之间的相关性研究  

Correlation between Peritumoral Edema and Its Histological Subtype in Meningiomas

作　　者：王骅[1] 刘莉[2] 尹波[1] 程海霞[3] 

机构地区：[1]复旦大学附属华山医院放射科,200040 [2]复旦大学附属肿瘤医院放射科,200032 [3]复旦大学附属华山医院病理科,200040

出　　处：《中国临床神经科学》2013年第3期296-300,共5页Chinese Journal of Clinical Neurosciences

摘　　要：目的探讨脑膜瘤病理类型与瘤周水肿之间的相关性。方法回顾性分析116例经病理证实的脑膜瘤病例,术前使用MRI Flair序列评价脑膜瘤瘤周水肿情况,结合脑膜瘤病理类型进行分析。结果在116例脑膜瘤患者中,无瘤周水肿46例(39.6%),有瘤周水肿70例(60.3%)。不同病理类型的脑膜瘤瘤周水肿的分级分析,差异有统计学意义(P<0.05),脑膜瘤瘤周水肿程度与病理类型具有相关性。血管瘤型、分泌型、不典型型及间变型脑膜瘤瘤周水肿明显;上皮型较纤维型脑膜瘤水肿明显。结论脑膜瘤瘤周水肿与病理学类型相关,对术前评价患者的预后及围手术期的风险有一定价值。Aim To determine the correlation between peritumoral brain edema （PTBE） and its histological subtypes. Methods 116 cases with intracranial meningioma diagnosed by pathology were retrospectively reviewed. These tumors and PTBE were assessed on MRI Flair sequences. Results In all 116 cases, MRI demonstrated that 70 cases （60.4%） were accompanied by PTBE and 46 cases （39.6%） were not accompanied by PTBE. There were statistically significant differences （P〈0.05） among the different subtypes of meningioma. The grade of PTBE was related with its histological subtype. Angiomatous, secretory, atypical and anaplastic subtypes tended to be accompanied by higher brain edema. Meningothelial subtype was associated with higher PTBE than fibroblastic subtype. Conclusion PTBE is related with its histological subtype, which may predict the risk of perioperative mortality and morbidity and prognosis before operation.

关 键 词：脑膜瘤 病理学 脑水肿 磁共振成像 

分 类 号：R739.45[医药卫生—肿瘤]