肠壁神经丛损伤和修复因素研究进展  

Progress in Study on Injury and Repair Factors of Enteric Plexus

作　　者：刘燕平[1] 范一宏[1] 吕宾[1] 

机构地区：[1]浙江中医药大学附属第一医院消化内科,310006

出　　处：《胃肠病学》2013年第5期313-316,共4页Chinese Journal of Gastroenterology

摘　　要：胃肠道壁内神经丛的主要组成部分为肌间神经丛和黏膜下神经丛。肠壁神经丛损伤可表现为神经变性、神经节细胞缺失等,导致胃肠道运动、感觉、分泌功能紊乱。本文就肠壁神经丛的损伤因素(如药物、炎症)和修复因素(如神经干细胞、神经营养因子、5-HT4受体激动剂)作一综述。Intramural plexus of gastrointestinal tract mainly contains the myenteric plexus and submucosal plexus. Injuries of enteric plexus may present as neural degeneration and loss of ganglion cells, etc. , which lead to motor, sensory and secretory impairment of the gut. In this article, the injury factors （e. g. drugs and inflammation） and repair factors （e. g. neural stem cells, neurotrophic factors, and 5-HT4 receptor agonists） of enteric plexus were reviewed.

关 键 词：肠神经系统 肠肌丛 损伤 修复 神经干细胞 神经生长因子类 受体 血清素 5-HT4 

分 类 号：R57[医药卫生—消化系统]