高危风险孕妇绒毛染色体异常发生率探讨  

The study of the incidence of chromosomal abnormalities in the villus samples of high-risk pregnant women

作　　者：李强[1] 孙淑梅[1] 

机构地区：[1]天津市第三中心医院,300170

出　　处：《河北医药》2000年第6期413-414,共2页Hebei Medical Journal

摘　　要：目的　探讨先兆流产、自然流产与染色体异常发生率之间的关系。方法　对 15 7例孕妇早期流产绒毛进行染色体分析。结果　有风险孕妇流产绒毛染色体异常发生率为 15 .5 2 % ,正常对照组染色体异常发生率为 5 .2 6% ,两组差异显著 (P <0 .0 5 )。结论　研究表明先兆流产、自然流产与染色体异常的发生有直接关系 ,在临床遗传咨询及产前诊断时应予以高度重视。Objective To study the relationship between threatened and recurrent abortion and the incidence of chromosomal abnormalities.Methods 157 samples of chorionic villus in early pregnancy were analyzed by cytogenetic method.Results The incidence of chromosomal abnormalities in the villus samples of high-risk pregnant women was 15.52%,while that of the control group was 5.26%.The difference between the two groups was significant(P<0.05).Conclusion The relationship between threatened and recurrent abortion and the incidence of chromosomal abnormalities is of significance,and it is very important in genetic consultation and antenatal diagnosis.

关 键 词：绒毛 核型分析 染色体异常 发生率 孕妇 

分 类 号：R714.2[医药卫生—妇产科学]