应用聚桂醇经BRTO治疗孤立性胃底静脉曲张23例  

Treatment of isolated gastric varices by balloon-occluded retrograde transvenous obliteration using lauromacrogol: An analysis of 23 cases

作　　者：赵东强[1] 姜慧卿[1] 马俊骥[1] 王晓经[1] 刘增品[2] 赵琳[2] 张楠[2] 

机构地区：[1]河北医科大学第二医院消化内科河北省消化病实验室河北省消化病研究所,河北省石家庄市050000 [2]河北医科大学第二医院导管室,河北省石家庄市050000

出　　处：《世界华人消化杂志》2013年第15期1412-1416,共5页World Chinese Journal of Digestology

摘　　要：目的:评价应用聚桂醇经球囊导管逆行经静脉栓塞(balloon-occluded retrograde transvenous obliteration,BRTO)治疗孤立性胃底静脉曲张(isolated gastric varices,IGV)的疗效及安全性.方法:回顾性分析2009-11/2012-09我院伴有胃肾分流的IGV患者23例,应用聚桂醇进行BRTO治疗,观察其疗效及安全性.结果:经BRTO治疗成功患者21例.术中3例患者发生低血压及窦性心动过缓,后经多巴胺及山莨菪碱等药物治疗及撤除球囊压迫后好转.术后无腹水及肝肾功能的加重.术后3mo胃镜复查静脉曲张消失13例,明显减轻6例,无改变2例.患者随访3-18mo,无消化系出血发生.结论:应用聚桂醇经BRTO治疗伴有胃肾分流的孤立性胃底静脉曲张,具有良好的临床疗效和安全性.AIM： To evaluate the efficacy and safety of lauromacrogol in treating isolated gastric varices by balloon-occluded retrograde transvenous obliteration （BRTO）. METHODS： The clinical data for 23 patients who were diagnosed with isolated gastric varices with gastrorenal shunt and treated by BRTO us ing lauromacrogol from November 2009 to September 2012 were retrospectively analyzed. The clinical efficacy, safety and complications of this procedure were evaluated. RESULTS： The procedure was successful in 21 cases. Hypotension and sinus bradycardia were observed intraoperatively in three cases and disappeared when the balloon was withdrawn. No complications such as ascites and hepatorenal function exacerbation occurred after the opera- tion. Endoscopic examination at 3 mo after the procedure showed that varices disappeared in 13 cases, remarkably decreased in size in 6 cases, and had no significant changes in 2 cases. During 3 to 18 mo of follow-up, no bleeding was observed. CONCLUSION： BRTO using lauromacrogol is effective and safe in treating isolated gastric varices with gastrorenal shunt.

关 键 词：孤立性胃底静脉曲张 球囊导管逆行经静脉栓塞 聚桂醇 胃肾分流 

分 类 号：R575.2[医药卫生—消化系统]