美洲凌霄花的化学成分研究  

Study on the chemical constituents from the flowers of Campsis radicans

作　　者：韩海燕[1] 褚纯隽[1] 姚士[1] 张健[1] 

机构地区：[1]苏州大学药学院,江苏苏州215123

出　　处：《华西药学杂志》2013年第3期241-243,共3页West China Journal of Pharmaceutical Sciences

基　　金：江苏高校优势学科建设工程资助项目(PAPD)

摘　　要：目的研究美洲凌霄花的化学成分。方法利用硅胶柱色谱、Sephadex LH-20凝胶柱色谱、反相柱色谱等手段对美洲凌霄花70%乙醇提物进行分离纯化,并通过理化性质和光谱数据鉴定其结构。结果从美洲凌霄花中分离得到11个化合物,分别为棕榈酸(Ⅰ)、十九烷酸(Ⅱ)、β-谷甾醇(Ⅲ)、鼠李柠檬素(Ⅳ)、芹菜素(Ⅴ)、柯伊利素(Ⅵ)、反式对羟基桂皮酸(Ⅶ)、咖啡酸(Ⅷ)、3-羟基-4-甲氧基-苯甲酸(Ⅸ)、原儿茶酸(Ⅹ)、胡萝卜苷(Ⅺ)。结论化合物Ⅰ～Ⅺ均首次从该植物分离得到,化合物Ⅰ、Ⅱ、Ⅳ、Ⅵ～Ⅹ为首次从该属植物中分离得到。OBJECTIVE To Study the chemical constituents from the flowers of Campsis radicans（L.）Seem.METHODS The compounds were extracted with 70% alcohol from the flower of Campsis radicans（L.）Seem,followed by isolation purification using silica gel,Sephadex LH-20,as well as reverse phase column chromatography.Their structures were identified on the basis of physicochemical properties and spectral analysis.RESULTS Eleven compounds were isolated and identified as hexadecanoic acid（Ⅰ）,n-nonadecanoic acid（Ⅱ）,β-sitosterol（Ⅲ）,rhamnocitrin（Ⅳ）,apigenin（Ⅴ）,chrysoeriol（Ⅵ）,trans-p-hydroxy cinamic acid（Ⅶ）,caffeic acid（Ⅷ）,3-hydroxy-4-methoxy-benzoic acid（Ⅸ）,protocatechuic acid（Ⅹ）and daucosterol（Ⅺ）.CONCLUSION Compounds Ⅰ-Ⅺ were isolated from the Campsis radicans（L.）Seem for the first time and compounds Ⅰ,Ⅱ,Ⅳ,Ⅵ-Ⅹ were isolated from the Campsis for the first time.

关 键 词：美洲凌霄花 分离鉴定 化学成分 

分 类 号：R914[医药卫生—药物化学]