同步化放疗结合清肺八味汤治疗局部晚期非小细胞肺癌的临床研究  

Clinical Observation of Qingfei Bawei Decoction Combined with Concurrent Chemoradiotherapy in Non-small Cell Lung Cancer

作　　者：吴树强[1] 袁国荣[1] 林白桦[1] 罗利民[1] 吕世良[1] 毕爱红[1] 贾勇士[1] 

机构地区：[1]浙江省人民医院,浙江杭州310014

出　　处：《中华中医药学刊》2013年第6期1275-1277,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：国家中医药管理局资助项目(201209);浙江省中医药管理局资助项目(2010ZR001)

摘　　要：目的:探讨同步化放疗结合清肺八味汤治疗局部晚期非小细胞肺癌(Non-small Cell Lung Cancer,NSCLC)患者的临床疗效。方法:53例接受治疗的患者,随机分入联合组,同步化放疗结合清肺八味汤治疗和对照组仅同步化放疗,评定疗效和不良反应。结果:联合组疗效及KPS评分优于对照组,中性粒细胞减少少于对照组,差异有统计学意义(P<0.05)。结论:同步化放疗结合清肺八味汤能有效减轻局部晚期非小细胞肺癌化放疗的不良反应,提高疗效和生存质量。Objective：To explore the clinical outcome of Qingfei Bawei Decoction combined with concurrent chemoradiotherapy in patients with non - small cell lung cancer （NSCLC）. Methods ： Fifty - three inpatients with NSCLC were randomly divided into Qingfei Bawei Decoction group which was treated with Qingfei Bawei Decoction combined with concurrent chemoradiotherapy and control group which was treated with single concurrent chemoradiotherapy. The responses and toxicities were compared between the two groups. Results ： In the short - term response it showed that Qingfei Bawei Decoction group responded better than control group（ P 〈 0.05 ）. The performance status of Qingfei Bawei Decoction group, according to KPS questionaire,was higher than that of control group （P 〈 0.05）. As to the neutropenia, Qingfei Bawei Decoction group suffered less than control group（P 〈 0. 05）. Conclusion：Qingfei Bawei Decoction combined with concurrent chemoradiotherapy can enhance clinical therapeutic effect, improve the quality of life and reduce the toxicities of patients with locally advanced NSCLC.

关 键 词：非小细胞肺癌 化放疗 清肺八味汤 

分 类 号：R734.2[医药卫生—肿瘤]