EORTC评分系统在2μm激光与TUR-Bt治疗非肌层浸润性膀胱癌预后预测中的对照研究  

A comparative study of recurrence and progression in non-muscle-invasive bladder tumor after 2 μm continuous-wave thulium laser or transurethral resection using european transurethral resection organization of research and treatment of cancer scoring syst

作　　者：湛炜璋 梁月有[2] 陈羽[1] 袁庆培 

机构地区：[1]广东省增城市新塘医院外三科,511340 [2]中山大学附属第一医院泌尿外科,广州510080

出　　处：《中华腔镜泌尿外科杂志（电子版）》2013年第3期6-9,共4页Chinese Journal of Endourology(Electronic Edition)

摘　　要：目的评估欧洲癌症研究与治疗组织风险评分表(EORTC)在2μm激光与经尿道膀胱肿瘤电切术(TUR-Bt)治疗非肌层浸润性膀胱癌(NMIBT)预后判断的价值。方法对2009年3月至2011年12月间在我院行经尿道膀胱肿物切除术的98例患者进行EORTC评分,其中56例患者行TUR-Bt术,42例行2μm激光肿瘤切除术,结合随访资料,回顾性分析EORTC在两种手术方式治疗NMIBT术后预测复发与进展方面的差异。结果 98例研究对象中1年内复发39例,其中TUR-Bt组23例(41.1%),2μm激光组16例(38.1%)。研究对象中1年内进展9例,其中TUR-Bt组6例(10.7%),2μm激光组3例(7.1%)。TUR-Bt组与2μm激光中实际复发或进展率与EORTC预测复发或进展率基本吻合,无统计学差异(P>0.05)。EORTC在两种手术术后预测复发与进展方面无统计学差异(P>0.05)。结论 EORTC预测体系能对NMIBT术后的临床预后进行较准确的预测,在2μm激光术中的应用价值,扩展了改预测体系的应用范围,是一种新的、极具潜力的预后判断手段。Objective To assess the clinical prognostic value of European organization of research and treatment of cancer scoring system （EORTC） for non-muscle-invasive bladder tumor （NMIBT） after 2 μm continuous-wave thulium laser or transurethral resection （TUR-Bt）. Methods Clinical data of 56 TUR-Bt cases and 42 2 μm continuous-wave thulium laser cases were scored with EORTC scoring system retrospectively, and confirmed the difference in recurrence and progression prediction of EORTC for NMIBT after 2 μm continuous-wave thulium laser and transurethral resection. Results There was no significant difference of recurrence and progression of NMIBT between the two groups （recurrence rate in 1 year： TUR-Bt group 41.1%, 2μm continuous-wave thulium laser group 38.1%; progression rate in 1 year： TUR-Bt group 10.7%, 2 μm continuous-wave thulium laser group 7.1%, P〉0.05）. The recurrence and progression predicting risk of EORTC in TUR-Bt group and 2μm continuous-wave thulium laser group were coordinated with the real risks, with no significant difference （P〉0.05）. No significant difference was found in recurrence and progression predicting risk of EORTC of the two groups（P〉0.05）. Conclusions The EORTC scoring system can predict prognosis of NMIBT accurately, and has a promising clinical value in 2 μm continuous-wave thulium laser for NMIBT. It is a novel prognosis estmation method with much potential.

关 键 词：非肌层浸润性膀胱癌 经尿道膀胱肿瘤电切术 2ΜM激光 欧洲癌症研究与治 疗组织风险评分表 

分 类 号：R737.14[医药卫生—肿瘤]