四川盐亭与河北磁县1988～2007年贲门癌发病趋势分析  

Incidence Trends of Gastric Cardia Carcinoma in Yanting County and Cixian County,1988～2007

作　　者：李军 何永明 江海东 陈君泽 宋国慧 陈志峰[3] 

机构地区：[1]盐亭县肿瘤研究所,四川绵阳621600 [2]河北磁县肿瘤医院,河北磁县056500 [3]河北医科大学第四医院肿瘤研究所,河北石家庄050011

出　　处：《中国肿瘤》2013年第5期344-349,共6页China Cancer

摘　　要：[目的]根据四川盐亭和河北磁县肿瘤登记处数据,比较1988～2007年中国两个不同地域食管癌高发区贲门癌发病趋势的变化。[方法]截取1988～2007年发病数据库ICD编码C16.0,组织学诊断比例76.4%～78.8%。贲门癌的发病采用y=α+βx+ε线性模型,计算年度变化百分比(APC)。[结果]四川盐亭1988年贲门癌中标率为11.04/10万,2007年17.66/10万;河北磁县则分别为7.62/10万和37.41/10万。四川盐亭贲门癌发病呈明显上升,男女合计贲门癌发病APC为5.89%,其中男性2.87%,女性2.84%,有统计学差异;河北磁县贲门癌发病的APC分别为7.66%、8.13%和6.46%(P=0.000)。[结论]中国两个不同地域食管癌高发区人群20年贲门癌发病均呈现明显的增长趋势,发病显著增高的原因与ICD编码规则和内镜的临床广泛应用关系密切。[Purpose] To compare incidence trends of gastric cardia carcinoma in two high risk areas of esophageal cancer from 1988 to 2007. [Methods] Extracting disease code of ICD C16.0 from 1988～2007 cancer database,the morphology verified cases accounted for 76.4%～78.8%. Incidence of gastric cardia carcinoma used linear model of y=α＋βx＋ε to calculate annual percentage change （APC）. [Results] The age-standardized incidence rates of gastric cardia carcinoma by China population in Yanting were 11.04/105 in 1988 and 17.66/105 in 2007; in Cixian the rates were 7.62/105 and 37.41/105 respectively. In Yanting,the incidence of gastric cardia carcinoma had an increasing trend,and the APC was 5.89% （2.87% for male and 2.84% for female）. In Cixian, the APC was 7.66% （8.13% for male and 6.46% for female）. [Conclusion] The incidences of gastric cardia carcinoma have obvious increasing trends both in Yanting and Cixian. It might correlate with coding rule of ICD and widespread using of endoscope.

关 键 词：贲门癌 发病 年度变化百分比 食管癌高发区 

分 类 号：R734.1[医药卫生—肿瘤]