D-手性肌醇的研究与开发  

The research and development of D-chiro-inositol

作　　者：张泽生[1] 裴雅[1] 高云峰[1] 孙久苓[1] 王芮[1] 

机构地区：[1]天津科技大学食品工程与生物技术学院,天津300457

出　　处：《中国食品添加剂》2013年第3期77-83,共7页China Food Additives

基　　金：天津市高等学校科技发展基金计划项目(20100609)

摘　　要：D-手性肌醇(D-chiro-inositol,DCI)是肌醇九种异构体中具有旋光性的一种。近年来人们研究发现DCI除了具有肌醇促进肝脏脂代谢功能外,还具有如胰岛素增敏作用,降血糖,改善多囊卵巢综合症(PCOS)患者的排卵情况,以及抗氧化、抗衰老、抗炎特殊的生理功能。因此,DCI可以作为医药、保健品原料以及膳食补充剂,具有广阔的开发前景。目前对于DCI的制取,主要采用化学合成和从自然资源中分离提取的方法,成本高且步骤较多。为了造福对广大的糖尿病、胰岛素抵抗的患者们,需要寻找到成本较低、耗费时间短、提取率高的制备DCI的方法。本文主要介绍肌醇的结构、DCI的功能研究、制备方法及产品开发。D-chiro-inositol（DCI） is a member of nine stereoisomers of inositol.It has the effect of promoting liver fat metabolism.Recently,DCI appears to have substantial beneficial effects on promoting insulin function,lowering blood sugar,increasing frequency of ovulation for patients with PCOS.It also has the function of anti-oxidation,anti-aging,and anti-inflammatory.Therefore,it can be used as drugs,raw materials of health products,and nutritional supplements which has a bright development prospect.Nowadays,the production of DCI is mainly made from either chemical synthesis or natural product extraction,which are expensive and time-consuming.Therefore,an inexpensive,less time consuming method for producing DCI can benefit many diabetes or patients with insulin resistance.In this paper,the research of D-chiro-inositol functions,and the process for preparation and the development of DCI are discussed.

关 键 词：D-手性肌醇 糖尿病 多囊卵巢综合症 生产D-手性肌醇 

分 类 号：TS202.1[轻工技术与工程—食品科学]