胸、乳径路腔镜甲状腺手术与传统颈部切口甲状腺手术对机体创伤的对比研究  

A comparative study on body trauma of chest-breast endoscopic thyroid surgery and the traditional neck incision thyroid surgery

作　　者：耿中利[1] 别克.扎提 杨乐[1] 单美慧[1] 马斌林[1] 

机构地区：[1]新疆医科大学附属肿瘤医院乳腺/头颈外科,乌鲁木齐830011

出　　处：《新疆医科大学学报》2013年第6期805-807,810,共4页Journal of Xinjiang Medical University

基　　金：乌鲁木齐市科学技术计划项目(Y09231001)

摘　　要：目的比较胸、乳入路腔镜甲状腺手术与传统颈部切口甲状腺手术对机体的创伤大小。方法将2009年1月-2010年12月收治的60例甲状腺良性肿瘤患者分为腔镜手术组(n=32例)和传统手术组(n=28例),对两组手术时间、出血量、术后引流量、术后并发症(术后颈部感觉、大出血、喉返神经损伤及喉上神经损伤、甲状旁腺损伤)、术后疼痛、血清白细胞介素-6、血清白细胞介素-2、C反应蛋白和肿瘤坏死因子-α及心理创伤等进行比较。结果与传统手术组比较,腔镜手术组手术时间较长,出血量较少,差异有统计学意义(P<0.05),两组术后引流量、术后出血、术后喉返神经损伤和喉上神经损伤及甲状旁腺损伤比较差异无统计学意义;两组术前1d、术后2h、术后1d及术后3d血清白细胞介素-2、C反应蛋白和肿瘤坏死因子-α值比较差异无统计学意义,两组术后2h、1d血清白细胞介素-6比较差异有统计学意义(P<0.05),腔镜手术组心理创伤明显小于传统手术组。结论腔镜甲状腺手术与传统甲状腺手术相比具有较多优势,是一种值得推广的手术方式。Objective To compare the wound size to human body between endoscopic thyroidectomy through chest and traditional one through neck. Methods Sixty cases with thyroid benign tumor, hospitalized from January 2009 to December 2010 were divided into endoscopic thyroidectomy group （n =32 cases） and traditional thyroid surgery group （n =28 cases） in respect of the patients＇ own will. The following aspects were compared between two groups： time of surgery, bleeding, quantity of fluid drainage, complications, pain, level of Interleukin 2 （IL-2）, Interleukin 6 （IL-6）, C-reactive protein （CRP）, tumor necrosis factor （TNF-α） which stand for stress reaction, psychological trauma. Results The operation time is longer in endoscopic group, but bleeding was less （P d0. 05）. No statistical significance were found between two groups in terms of fluid drainage, complications, pain, level of IL-2, IL-6, CRP, TNF-α. The level of IL 6 in serum was statistical significant between the time of 2 hours and 1 day after surgery. Conclusion Endoscopic thyroidectomy is worthy of being applied for its superiorities compared to traditional surgery.

关 键 词：腔镜甲状腺手术 传统手术 创伤 

分 类 号：R736.1[医药卫生—肿瘤]