内蒙古准格尔旗35岁及以上人群卒中患病和血脂水平的现况调查  

Present situation investigation of stroke prevalence and lipid levels in a population of ≥ 35 years old in Jungar Banner,Inner Mongolia

作　　者：武霞[1] 宋军平[1] 江名芳[2] 王智光[2] 高春桃 赵世刚[2] 吉沛[1] 

机构地区：[1]内蒙古医科大学附属人民医院神经内科,呼和浩特010020 [2]内蒙古医科大学附属医院神经内科 [3]内蒙古监狱管理局第一医院

出　　处：《中国脑血管病杂志》2013年第5期244-249,共6页Chinese Journal of Cerebrovascular Diseases

基　　金：内蒙古自治区自然科学基金资助项目(2012MS1151)

摘　　要：目的探讨内蒙古准格尔旗≥35岁人群的卒中患病情况和血脂水平的关系。方法采用整群随机抽样方法,抽取内蒙古准格尔旗常住居民,进行统一体格检查、问卷调查和实验室检查,收集资料并进行统计学分析。结果①2007年4—12月本次流行病学研究共计调查72350人,应答率为88.7%,其中非卒中69762人,卒中2588例,卒中患病率为3.58%。②35～44岁、45～54岁、55～64岁、65～74岁和≥75岁年龄组卒中患病率分别为0.46%、1.46%、4.68%、7.35%和6.28%,随着年龄增长而上升(≥75岁组略为下降),差异有统计学意义(P<0.01)。③脑梗死(χ2=448.361,P<0.01)、脑出血(χ2=105.243,P<0.01)患病率均随年龄增长而上升。45～54岁年龄组男性脑梗死患病率(1.27%)高于女性(0.96%);55～64岁年龄组男性脑出血患病率(1.35%)高于女性(1.00%),差异均有统计学意义(P<0.01)。④女性血清胆固醇(TC)、三酰甘油(TG)的平均值高于男性,差异均有统计学意义(P<0.05)。>55岁年龄组女性TC、TG水平高于同年龄段男性,差异均有统计学意义(P<0.05)。⑤脑梗死发生率均随TC、TG水平的升高而增加,与正常水平组比较,其相对危险性亦升高(均P<0.01)。TC≥5.68mmol/L患者的脑出血发生率高于TC正常水平者,相对危险性亦提高(P<0.01)。结论内蒙古准格尔旗≥35岁人群卒中患病率为3.58%,患病率随年龄增长而升高;男性在45～54岁、55～64岁年龄段的脑梗死、脑出血患病率高于同年龄段的女性;>55岁年龄组女性的TC、TG水平高于同年龄段男性;脑梗死发生率均随TC、TG水平的升高而增加。Objective To investigate the relationship between the stroke prevalence and lipid levels in a population of ≥35 years old in Jungar Banner, Inner Mongolia. Methods A cluster random sampling method was used to extract the permanent residents in Jungar Banner, Inner Mongolia for unified physical examination, questionnaire survey and laboratory tests, and the data were collected for statistical analysis. Results ①The number of subjects selected from the epidemiological survey in the relevant study were 72 350, the response rate was 88.7% , and 69 762 of them had no stroke and 2588 of them suffered from stroke. The stroke prevalence was 3.58%. ②In the age groups of 35 to 44, 45 to 54, 55 to 64, 65 to 74, and ≥75, the prevalences of stroke were 0.46%, 1.46%, 4.68%, 7.35% and 6.28%, respectively. They increased with age. The differences were statistically significant （ P 〈 0.01 ）. ③The prevalences of cerebral infarction （X2 = 448. 361 ;P 〈 0.01 ） and intracerebral hemorrhage （X2 = 105. 243 ;P 〈0.01 ） all increased with age. In the 45 to 54 age group, the prevalence of cerebral infarction in men （ 1.27% ） was higher than that in women （0.96%） ; in the 55 to 64 age group, the prevalence of intracerebral hemorrhage in men （ 1.35% ） was higher than that in women （ 1.00% ） , and the difference was statistically significant （P 〈 0.01 ）. ④The mean serum total cholesterol （TC） and triglyceride （TG） levels in women were higher than those in men, and the differences were statistically significant （ P 〈 0.05 ）. In the 〉 55-year-old age group, the TC and TG levels in women were higher than those in men of the same age group, and the differences were statistically significant （P 〈 0.05 ）. ⑤The incidence of cerebral infarction increased with the increased levels of TC and TG. The risk also increased as compared to the group with normal levels （ P 〈 0.01 ）. The incidence of intracerebral hemorrhage of the TC level ≥ 5.68 mmol/L was higher than that in

关 键 词：总胆固醇 三酰甘油 卒中 流行病学研究 

分 类 号：R743.3[医药卫生—神经病学与精神病学]