妊娠合并重症肌无力13例临床分析  

Clinical analysis on 13 patients with myasthenia gravis and pregnancy

作　　者：谭金凤[1] 余利云[1] 

机构地区：[1]中山大学附属第一医院妇产科,广州市510080

出　　处：《实用医学杂志》2013年第12期1984-1987,共4页The Journal of Practical Medicine

摘　　要：目的:分析妊娠合并重症肌无力(MG)患者妊娠期间MG病情变化、MG对妊娠结局及新生儿的影响。方法:对本院收治的13例妊娠合并MG患者资料进行回顾性分析。结果:1例患者早孕6周选择终止妊娠,2例(16.7%)妊娠期间MG病情加重,10例(83.3%)病情稳定。无一例出现早产、胎膜早破等并发症。12例患者均接受剖宫产处理,其中有产科指征者4例。3例(25%)新生儿出现短暂性MG表现,经处理均获得缓解。结论:妊娠期间MG患者病情多变难预测,MG对妊娠无明显不良影响。新生儿可出现短暂性MG表现,经处理可获缓解。Objective To analyze the condition of myasthenia gravis （MG） during pregnancy and the effects of MG on the outcome of pregnancy and the neonate. Methods Clinical data of 13 patients with MG and pregnancy were retrospectively analyzed. Results 1 case with 6 weeks of pregnancy chose to terminate the pregnancy, exacerbation of MG occurred in 2 cases （16.7%）, while 10 cases （83.3%） showed no change in disease activity. No complication of preterm labor or premature rupture of membrane occurred. 12 cases received cesarean section, among which 4 cases had indications. 3 neonates （25%） showed signs of transient neonatal MG. Conclusion The course of MG during pregnancy is unpredictable, and MG has no relevant adverse effect on Ihe course of pregnancy. Infants born to MG mother would show signs of neonatal MG, but it is self-limited.

关 键 词：重症肌无力 妊娠 新生儿 

分 类 号：R746.1[医药卫生—神经病学与精神病学] R714.25[医药卫生—临床医学]