Multiple intron gain and loss events occurred during the evolution of Cenp-A gene  

作　　者：FAN XinYu YU Li XU HuaiLiang LI Ying 

机构地区：[1]College of Animal Science and Technology,Sichuan Agricultural University [2]Laboratory for Conservation and Utilization of Bio-resource,Yunnan University [3]Key Laboratory for Animal Genetic Diversity and Evolution of High Education in Yunnan Province,Yunnan University [4]Institute of Animal Breeding and Genetics,Sichuan Agricultural University

出　　处：《Chinese Science Bulletin》2013年第17期2174-2178,共5页

基　　金：supported by the National Natural Science Foundation of China (30970383);Program for New Century Excellent Talents in University (NCET)

摘　　要：Centromere protein A(CENP-A) is a histone H3 like protein,and it plays a very important role in chromosomal segregation during mitosis and meiosis.The analyses on the exon-intron organization of the Cenp-A gene in representative genomes revealed that multiple intron gain and loss events have occurred during the evolution of Cenp-A gene in opisthokonta(common ancestor of fungi and animals).Moreover,our results revealed that at least two positions were conserved in the intron gain and loss events during the evolution of the Cenp-A gene.Centromere protein A （CENP-A） is a histone H3 like protein, and it plays a very important role in chromosomal segregation during mitosis and meiosis. The analyses on the exon-intron organization of the Cenp-A gene in representative genomes revealed that multiple intron gain and loss events have occurred during the evolution of Cenp-A gene in opisthokonta （common ancestor of fungi and animals）. Moreover, our results revealed that at least two positions were conserved in the intron gain and loss events during the evolution of the Cenp-A gene.

关 键 词：进化过程 基因组 事件 损失 组蛋白H3 染色体分离 分裂过程 有丝分裂 

分 类 号：S863[农业科学—野生动物驯养]