国内系统评价纳入标准对随机试验的界定差异有可能导致偏倚  

Potential Bias Due to the Definition of RCTs for Inclusive Criteria of Systematic Reviews Published in Chinese Journals

作　　者：张质钢[1,2] 王小虎[1,2,3] 张秋宁[3] 

机构地区：[1]兰州大学循证医学中心,兰州730000 [2]兰州大学第一临床医学院,兰州730000 [3]甘肃省肿瘤医院,兰州730050

出　　处：《中国循证医学杂志》2013年第6期764-767,共4页Chinese Journal of Evidence-based Medicine

基　　金：重离子等射线治疗肿瘤研究科技创新团队建设计划(编号:098TTCA009)

摘　　要：系统评价纳入标准的制定对系统评价质量和结果的可靠性具有重要意义,而目前中文期刊发表的基于随机对照试验的系统评价中,由于纳入标准对随机试验的界定存在差异,可能导致不完全或不公平的纳入,再加之国内随机试验的质量相对较差,从而产生偏倚的可能。本研究通过抽样分析国内系统评价纳入标准对随机试验界定和实际纳入随机试验类型的现状,找出存在的问题并寻求解决的办法。The formulation of inclusive criteria is very important for the quality of systematic reviews as well as the reli- ability of results. However, among the systematic reviews based on randomized controlled trials （RCTs） published in Chinese periodicals, there are differences existing in the definition of inclusive criteria of RCTs, which may lead to the incomplete or inequitable inclusion. In addition, the relatively lower quality of domestic RCTs may also cause the possibility of bias. In this study, sampling analysis is applied to assess the current situation of both the RCTs definition for inclusive criteria of domestic systematic reviews and the types of practically included RCTs, so as to figure out the existing problems,

关 键 词：偏倚 系统评价 META分析 纳入标准 随机对照试验 

分 类 号：R-03[医药卫生]