鼠神经生长因子联合免疫球蛋白治疗儿童格林-巴利综合征的临床疗效  

Therapeutic effects of mNGF and IVIG cure for the children with guillain-barre syndrome

作　　者：陈桃[1] 郭渠莲[1] 杨义玲[1] 税利琴[1] 

机构地区：[1]泸州医学院附属医院儿科,四川泸州646000

出　　处：《重庆医学》2013年第17期1960-1961,共2页Chongqing medicine

摘　　要：目的观察鼠神经生长因子(mNGF)联合免疫球蛋白(IVIG)治疗儿童格林-巴利综合征(GBS)的临床疗效。方法 92例格林-巴利综合症患儿分为常规组、mNGF组,常规治疗组43例采用IVIG静脉滴注及交替肌内注射维生素B12注射液和加兰他敏治疗,mNGF组49例则在常规治疗组基础上加用mNGF注射治疗,治疗1个月后进行疗效判定。结果两组在肌力评分改善、愈显率等方面比较差异有统计学意义(P<0.01)。结论 mNGF联合IVIG可以显著提高儿童GBS的临床疗效。Objective To observe the clinical effects of mouse nerve growth factor（mNGF）combine with intravenous immunoglobulin（IVIG）cure on the children with GBS.Methods 92cases children with GBS were divided into two groups（routine treatment group and mNGF group）,routine treatment group（43cases）was treated by intravenous immunoglobulin and vitamin-B12、galantamine intramuscular injection.mNGF group（49cases）added mNGF injection on the basic of routine treatment group.Then observed the therapeutic efficacy.Results There was significant difference in muscle strength score,treatment effect（P0.01）between two groups.Conclusion The treatment of mNGF combined with IVIG can improve the clinical curative effect of children GBS significantly.

关 键 词：格林-巴利综合征 鼠神经生长因子 免疫球蛋白类 静脉内 治疗结果 

分 类 号：R745.43[医药卫生—神经病学与精神病学]