针刺治疗腹泻型肠易激综合征的实验研究进展  

Experimental Research Progress of Acupuncture for Irritable Bowel Syndrome-Diarrhea

作　　者：任驰[1] 牟建蛟[1] 周思远[1] 钟峰[1] 李瑛[1] 

机构地区：[1]成都中医药大学针灸推拿学院,四川成都610075

出　　处：《辽宁中医杂志》2013年第6期1266-1269,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家重点基础研究发展计划(973计划)资助项目(2011CB505205)

摘　　要：肠易激综合征是临床常见病和多发病,其病因和发病机制有肠道动力异常、内脏高敏感性、神经-免疫-内分泌网络调控和脑肠轴互动功能异常等多种学说,现代医学迄今尚缺乏疗效肯定的药物,对多予对症治疗。作者通过检索和分析近年来针刺治疗腹泻型肠易激综合征实验研究文献,发现目前针刺对腹泻型肠易激综合征调节机制的研究偏于单一化,多种机制之间的调控关系没有进行深入探讨,有关针刺作用的中枢机制以及信号通路的研究都还需进一步深入。今后的研究应侧重针刺对各机制之间相互关系的阐释,加强性激素以及情志因素对其关键机制影响的研究,使针刺作用机制的研究更加全面系统,从而更好地服务于临床。Irritable bowel syndrome （IBS） - diarrhea is a common and frequently-occurring disease. Its etiology and pathogenesis experienced intestinal motility disorders, visceral hypersensitivity, nerve-immune-endocrine network control and abnormal brain-gut axis interactive features in several stages, as yet modern medicine is lack of effective drugs, and always just gives symptomatic treatment. By inspecting China Academic Journal （CNKI）, we screened for experimental research literature of acupuncture therapy for IBS-diarrbea in recent years, analyzed and summarized the current situation in the included literatures. It showed that the current regulatory mechanisms of acupuncture treatment for IBS-diarrhea in the study were somewhat uniform, the regulation of relations between variety of mechanisms were not examined in depth. It is proposed that the central mechanisms of acupuncture role and signaling pathways need to be further explored ,future research should focus on the mechanism of acupuncture for the relationship between interpretation,and strengthening its key mechanisms of the sex hormones and emotional factors. What＇s more, it can make the mechanism of acupuncture further research to serve the clinic better.

关 键 词：肠易激综合征 针刺疗法 实验研究 

分 类 号：R57[医药卫生—消化系统]