76例外阴癌临床特征及预后影响因素分析  

Clinical Features and Analysis of Prognostic Factors of 76 Cases of Vulvar Carcinoma

作　　者：牛静[1,2] 郑曙民[2] 

机构地区：[1]山西医科大学,山西太原030001 [2]山西省肿瘤医院

出　　处：《中国医学创新》2013年第17期122-124,共3页Medical Innovation of China

摘　　要：目的:分析外阴癌临床特征及预后影响因素。方法:回顾性分析2000年1月-2008年12月山西省肿瘤医院收治的76例外阴癌患者的临床病理资料。结果:临床分期、病理分化程度及腹股沟淋巴结转移为外阴癌的预后影响因素。Ⅰ、Ⅱ、Ⅲ、Ⅳ期3年生存率分别为84.6%、75%、37.5%、60%(3/5),高、中、低分化3年生存率分别为81.8%、62.9%、33.3%,死亡风险为2.261,说明肿瘤分级每增加一级,死亡风险增加为原来的2.261倍。有淋巴结转移的死亡风险是没有淋巴结转移的3.065倍。结论:病理分化程度及腹股沟淋巴结转移为外阴癌的独立预后影响因素。应做到早发现、早诊断,配合正规的治疗是提高外阴癌生存率的关键。Objective： To study the clinical and pathological features of Patients with vulvar carcinoma, and elplore the risk factors of vulvar carcinoma prognosis.Method： From January 2000 to December 2011, 76 patients with vulvar carcinoma from Shanxi Tumor Hospital were eligible for analysis.Result： Clinical stage, histologic grading, lymph node metastasis, were found to be associated with the prognosissurvival. The 3 years Survival rates of Stage,Ⅰ、Ⅱ、Ⅲ、Ⅳ were 84.6%, 75%, 37.5%, 60% （ 3/5 ） .The 3 year Survival rates of Well, middle, poor differentiation were 81.8%, 62.9%, 33.3%, the risk of mortalitywas2.261, indicated with the histologic grading increase 1 stair, the the risk of mortality increased by 2.261 times, the risk of mortality in patients of lymph node metastasis was 3.065 times higher than that in patients of without lymph node metastasis. Conclusion： Histologic grading and lymph node metastasis are independent prognostic factors.Therefore, the earlier found, the earlier diagnosis, and standarded therapy are the key point to improve the survival rates of vulvar carcinoma.

关 键 词：外阴癌 临床特征 预后 

分 类 号：R737.35[医药卫生—肿瘤]