一种可多次取样的新型活检穿刺针的研制  

Development Of A Multiple Sampling Biopsy Needle

作　　者：闫涛 王争明[2] 武涧松 侯羿 李海英[5] 李峰生[6] 韩振川 申颖[8] 

机构地区：[1]第二炮兵总医院普通外科 [2]第二炮兵总医院放射科 [3]第二炮兵总医院感染性疾病科 [4]第二炮兵总医院医学工程科 [5]第二炮兵总医院口腔科 [6]第二炮兵总医院中心实验室 [7]解放军第96274部队修配厂卫生所 [8]第二炮兵总医院医务部

出　　处：《中国医学装备》2013年第6期48-50,共3页China Medical Equipment

摘　　要：目的:设计一种穿刺后可多次获取活组织标本、兼备快速止血以及预防肿瘤针道转移功能的新型活检针。方法:将20只成功接种VX2肝癌细胞株的实验兔随机分为A组和B组,A组使用新型活检针,B组使用PRECISA活检针。比较两组首次穿刺成功率、穿刺活检组织量、病理诊断结果以及穿刺并发症发生率。结果:A组首次穿刺成功率高于B组,分别为90%和70%;A组较B组可明显获取更多的条状活检组织,分别为100%和80%;病理示"严重挤压变形细胞,未能定性"而影响诊断者仅见于B组;A组出血、肿瘤针道转移发生率低于B组。结论:新型活检针弥补了现有活检针的不足,其应用前景广阔。Objective： Design a new type of biopsy needle which can gain striped structures repeatedly, stop bleeding and prevent tumor metastasis. Methods： Twenty rabbits with VX2 liver tumour carried on puncture biopsy under the CT guidance which ~tivided in two groups randomly. The multiple sampling biopsy needle was used in group A（10 examples） and Precisa biopsy needle used in group B （10 examples）. The difference of puncture success rate of first time, organization quantity, pathological diagnosis result and ~the incidence of puncture complication were compared between two groups. Results： The first time puncture success rate was higher in group A than in B： 90%（9/10）and 70%（7/10）respectively. More striped structures were gained obviously in group A＂ than in group ＂B＇（lOO0/o-（l~）/-10i-an-d-8bo/0（8/lO） respectively）. The pathological diagnosis ＂serious extrusion amoebocyte and nature undetermined＂only occurred in group B.The incidence of hemorhage and tumor metastasis in group A was lower than group B（P〈0.05）. Conclusion： The new type biopsy needle compensate the deficiency of the existing biopsy needle and has widely application prospect.

关 键 词：活检针 体层摄影术 X线计算机 活组织检查 CT导向 

分 类 号：R361.2[医药卫生—病理学]