痰和纤维支气管镜刷片细胞学检查在肺癌诊断中应用  

Application of sputum and bronchial brushing cytology in diagnosis of lung cancer

作　　者：王静[1] 

机构地区：[1]蚌埠医学院第一附属医院检验科,安徽蚌埠233004

出　　处：《淮海医药》2013年第4期297-299,共3页Journal of Huaihai Medicine

摘　　要：目的探讨痰和纤维支气管镜刷片细胞学检查在肺癌诊断中的意义。方法选取我院256例痰和纤维支气管镜检查的肺癌病例,分析痰和纤维支气管镜刷片细胞学检查的灵敏度和分型的准确性。进而评价细胞学检查在肺癌诊断中的价值。结果痰液细胞学在检测中的灵敏度为46.0%,纤维支气管镜刷片细胞学的灵敏度为62.5%。痰液细胞分型诊断与组织学的符合率鳞癌为64.4%、腺癌为76.2%、小细胞癌为87.0%。纤维支气管镜刷片细胞学分型诊断与组织学符合率鳞癌为85.1%、腺癌为81.0%、小细胞癌为97.8%。结论纤维支气管镜刷片细胞学在肺癌诊断方面具有较高的灵敏度和重要的应用价值。痰液细胞学灵敏度较低,但可作为纤支镜检查阴性而又不能耐受纤支镜检查肺癌患者的补充手段。Objective To explore the diagnostic value of sputum and bronchial brushing cytology in the diagnosis of lung cancer.Methods 256 patients with lung cancer were retrospectively analyzed.Both sputum analysis and bronchoscopic cytology were employed to all patients.The sensitivity and cytotyping accuracy of sputum and brush methods were analyzed.Results The sensitivity of sputum cytology and that of bronchial brushing cytology were 46.0% and 62.5% respectively.The cytotyping accuracy was 64.4% in squamous carcinoma,76.2% in adenocarcinoma and 87.0% in small cell carcinoma.The cytotyping accuracy for brush method was 85.1% in squmaous carcinoma,81.0% in adenocarcinoma and 97.8% in small cell carcinoma.Conclusion Bronchial brushing cytology shows a high sensitivity in the diagnosis of lung cancer.Sputum cytology can be performed as an adjunct to the bronchoscopic techniques.Both methods provide a reliable cytotyping diagnosis.

关 键 词：肺肿瘤 痰液细胞学 纤维支气管镜 刷片 诊断 

分 类 号：R734.2[医药卫生—肿瘤]