儿童与成年人甲状腺结节患病率对比研究  

A comparative study of prevalence of thyroid nodules in children with that in adults

作　　者：陈莹[1] 杨年忠[2] 杨文渊[3] 周金水[4] 

机构地区：[1]浙江省台州医院内科,临海317000 [2]台州市椒江区疾病预防控制中心慢病科,318000 [3]广西医科大学在读硕士研究生,南宁530021 [4]浙江省疾病预防控制中心环境与健康监测所,杭州310051

出　　处：《中华内分泌代谢杂志》2013年第6期512-514,共3页Chinese Journal of Endocrinology and Metabolism

摘　　要：按人口容量比例抽样法（PPS），以某中心小学为调查点，以某村20-80岁居民为成人对照，采用横断面调查方法，B超检查儿童甲状腺容积与结节，砷铈催化分光光度测定方法检测尿碘，直接滴定法测定盐碘含量。共调查6-12岁儿童180人，甲状腺肿大2例，肿大率1.11%，发现甲状腺结节16例，患病率8.89%，男生3例，患病率3.45%（n=87），女生13例，患病率13.98%（n=93），女生患病率大于男生（x2=6.154,P=0.015）。该村儿童期患病率低，成人甲状腺结节患病率24.51%，2组差异有统计学意义（X2=17.386,P=0.001），且随年龄增长，甲状腺结节患病率逐渐增高。With populational proportional sampling（PPS） method in Baigt,, village, one central primary school was seleeled, and villagers aged 20-80 in nearly village were chosen as control. Cross-seetional survey methodology was employed, B-type uhrasonography was used to determine thyroid volume and nodule of children. Arsenic eerium eatalytie spectrophotometrie assay was employed to deteet urinary iodine. A direct titration measuremenl was used to determinate iodine content in salt. 180 children aged 6-12 were surveyed, 2 eases of goiter were found 1. 11% ）. 16 eases of thyroid nodules were diseovered （ 8.89 % ） , including 3 boys （ 3.45 % , n= 87 ） and 13 girls（ 13.98%, n=93）. Girls had a higher prevalence than boys（x2=6. 154, P=0.015）. The prevalence of thyroid nodules in that village was 24. 51% , being statistically signifieant between 2 groups （X2 = 17. 368, P = 0. 001 ） , and increasing with the age.

关 键 词：碘 甲状腺肿 甲状腺结节 尿碘 碘盐 儿童 成年人 流行病学研究 

分 类 号：R5[医药卫生—内科学]