一氧化氮在急性胰腺炎中的作用  

Action of Nitric oxide on the acute pancreatits

作　　者：张剑[1] 余秀专[1] 周怀文[1] 

机构地区：[1]贵阳医学院附院普外科,550004

出　　处：《贵州医药》2000年第9期515-516,共2页Guizhou Medical Journal

基　　金：贵州省卫生厅科研基金资助课题

摘　　要：目的探讨一氧化氮 (NO)和肿瘤坏死因子 (TNF)在急性胰腺炎中的作用。方法采用比色法和平衡法分别对急性水肿型胰腺炎 (AEP)患者 30例和急性坏死型胰腺炎 (ANP)患者 2 0例以及正常人对照组 30例外周血进行NO和TNF水平检测。结果AEP和ANP组患者NO和TNF水平显著高于对照组 (P <0 0 5 ) ;ANP组NO和TNF水平显著高于AEP组。结论NO和TNF在急性胰腺炎的发生、发展中起重要作用。Objective To study the relationship between nitric oxide(NO),tumor necrosis factor(TNF) and acute pancreatitis. Methods The serum level of NO and TNF was measured in 30 patients with acute edematous pancreatitis (AEP) and 20 cases with acute necrosis pancreatitis (ANP). Results The serum level of NO and TNF in both AEP and ANP groups was significantly higher than the normal control group( P <0 05). Significant increase was noted in serum NO and TNF in ANP guoup than the AEP group( P <0 05).Conclusion The NO and TNF play imoprtant role in the induction of acute pancreatitis.

关 键 词：急性胰腺炎 一氧化氮 肿瘤坏死因子 AEP ANP 

分 类 号：R576[医药卫生—消化系统]