视网膜电图振荡电位的提取及定量技术的进展  

Extraction and measurement of electroretinogram oscillatory potentials

作　　者：郑昌伟[1,2,3] 雷博[1,2,3] 

机构地区：[1]重庆医科大学附属第一医院眼科,重庆400016 [2]眼科学重庆市市级重点实验室,重庆400016 [3]重庆市眼科研究所,重庆400016

出　　处：《中华眼视光学与视觉科学杂志》2013年第6期382-384,共3页Chinese Journal Of Optometry Ophthalmology And Visual Science

摘　　要：视网膜电图振荡电位（OPs）是叠加在视网膜电图（ERG）中b波上升支的数个高频率、有节律的小波。因为OPs是反应视网膜内层功能的一个敏感指标，国际临床视觉电生理学会（ISCEV）把它列入5项检查指标之一。OPs的准确采集取决于滤波器的正确使用，然而由于提取OPs时滤波器参数设置不当，很多研究未能将OPs中所包含的ERG低频率成分剔除，得到的并非是纯净的OPs。此外，传统的OPs计量方法是将OPs各子波振幅累加而得。这种测量方法受低频率成分的干扰导致可靠性和重复性差，明显影响OPs的分析。正确设置滤波器可得到纯净的OPs。用积分的方法计算OPs信号频谱曲线下的面积即振幅能量的方法可准确计量0Ps。Oscillatory potentials （OPs） are a group of regular, high frequency wavelets superimposed on the ascending limb of the electroretinogram （ERG） b-wave. The ERG standard recommended by the International Society for Clinical Electrophysiology of Vision （ISCEV） suggests oscillatory potentials are one of the five routine examinations because OPs are sensitive functional indicators of the inner retina. Extraction of pure OPs depends largely on using filters correctly. However, many OPs studies fail to remove the low frequency components of the ERG simply because of inappropriate filter settings. In addition, the traditional method of OPs measurement summarizes the amplitude of each single wavelet. The reliability and repeatability of the method are significantly compromised by the low frequency contaminants. To extract pure OPs, it is essential to set the filter parameters appropriately. Calculating the area below the single-sided frequency spectrum curve by integration provides an accurate assessment of the total power of OPs.

关 键 词：视网膜电描记术 振荡电位 视网膜 

分 类 号：R77[医药卫生—眼科]