肺错构瘤的临床病理学分析  

Clinical and pathological analysis of pulmonary hamartoma

作　　者：李伟华[1] 陈健[2] 夏康[1] 阮荣和[1] 高源统[3] 

机构地区：[1]温州医学院附属第三医院病理科,浙江温州325200 [2]余姚市人民医院病理科,浙江宁波315400 [3]温州医学院附属第三医院放射科,浙江温州325200

出　　处：《温州医学院学报》2013年第6期391-393,共3页Journal of Wenzhou Medical College

摘　　要：目的:探讨肺错构瘤的临床病理学特征,以助于临床正确诊断与治疗。方法:回顾性分析21例肺错构瘤的临床表现、影像学特征、组织学特点、免疫组化表型,总结肺错构瘤的诊断要点。结果:肺错构瘤包括肺内型、支气管内型及混合型(肺内合并支气管内型错构瘤)。肺内型位于肺外周,大多数没有明显临床症状,肿瘤通常境界清楚;支气管内型位于支气管内,呈息肉状。镜下由不同比例的间叶组织和呼吸型上皮混杂组成,有者软骨和脂肪成分很少甚至缺乏。结论:肺错构瘤是最常见的良性肺肿瘤,有多种临床类型和组织学类型,影像上未见脂肪或软骨密度亦不能排除错构瘤的诊断,需结合临床表现、影像学资料及病理检查以确诊。Objective： To explore the clinical and pathological features of pulmonary hamartoma, in order to help clinical diagnosis and treatment correctly. Methods： Twenty-one cases of pulmonary hamartoma were analyzed retrospectively based on clinical manifestations, imaging features, histological features, immunohistochemical phenotype, and summarized key points of pulmonary hamartoma diagnosis. Results： There were several types of pulmonary hamartoma, including intrapulmonary type, bronchial type and mixed type （intrapulmonary with endobronchial）. The intrapulmonary type located in the peripheral lung had no obvious clinical symptoms, and normally had clear boundary; the bronchial type located in bronchus with shape of polypus, microscopically consisted of different proportions of mesenchymal tissue and respiratory epithelium, and someone mixed cartilage with.little fat even with no fat. Conclusion： Pulmonary hamartoma is the most common benign lung tumor, there are a variety of clinical types and histological types, no fat or cartilage density image cannot rule out the diagnosis of hamartoma, its clear diagnosis must be combined with clinical manifestations, imaging data and pathological examination.

关 键 词：肺 错构瘤 病理学 临床 

分 类 号：R734.2[医药卫生—肿瘤]