含漱利多卡因、庆大霉素、地塞米松混合液对百草枯中毒所致口腔黏膜炎的影响  

Effects of lidocaine gargle, gentamicin, dexamethasone mixture on oral mucositis caused by paraquat poisoning

作　　者：陈绍娟[1] 余权珍[1] 黄柳清[1] 

机构地区：[1]广东医学院附属医院消化内科, 湛江524001

出　　处：《中国实用护理杂志》2013年第18期22-23,共2页Chinese Journal of Practical Nursing

基　　金：广东省湛江市科技攻关项目（2012C3105037）

摘　　要：目的观察含漱利多卡因、庆大霉素、地塞米松混合液对百草枯中毒所致口腔黏膜炎程度及其治愈时间的影响。方法将61例百草枯中毒患者随机分为实验组31例和对照组30例；实验组给予利多卡因、庆大霉素、地塞米松混合液含漱，对照组给予地塞米松稀释液含漱，观察2组患者口腔黏膜炎的程度、治愈的时间并进行比较。结果实验组与对照组口腔黏膜炎的程度以及口腔黏膜炎治愈时间有显著差异。结论含漱利多卡因、庆大霉素、地塞米松混合液能减轻百草枯中毒患者口腔黏膜炎程度，加速口腔黏膜炎愈合，减轻患者的痛苦，值得临床推广。Objective To observe the effect of lidocaine gargle, gentamicin, dexamethasone mix- ture on degree and cure time of oral mucositis caused by paraquat poisoning. Methods 61 patients with paraquat poisoning were randomly divided into the experimental group （31 cases） and the control group （30 cases）; the experimental group was given lidocaine, gentamicin, dexamethasone mixture gargle, the control group was given dexamethasone dilution as gargle. The degree of oral mucositis and healing time were compared between two groups. Results There was significant difference in degree of oral mucositis and healing time between the experimental group and the control group. Conclusions Lido- caine gargle, gentamicin, dexamethasone mixture gargle can reduce degree of oral mucositis and hasten healing in patients with paraquat poisoning. It can alleviate the suffering of patients, and is worthy of clinical application.

关 键 词：利多卡因 庆大霉素 地塞米松 百草枯 口腔黏膜炎 

分 类 号：R78[医药卫生—口腔医学] R5[医药卫生—临床医学]