1例髓细胞肉瘤/AML患者异基因造血干细胞移植后肾上腺占位的多学科诊疗  

Multidisciplinary team diagnosis and therapy for a myeloid sarcoma/AML patient with adrenal mass after allogeneic hematological stem cell transplantation

作　　者：王亚非[1] 李倩[1] 徐文贵[2] 肖建宇[3] 庞青松[4] 杨庆[5] 张翼鷟[1] 

机构地区：[1]天津医科大学附属肿瘤医院血液肿瘤科,天津市肿瘤防治重点实验室,天津市300060 [2]天津医科大学附属肿瘤医院PET-CT室,天津市300060 [3]天津医科大学附属肿瘤医院影像科,天津市300060 [4]天津医科大学附属肿瘤医院放疗科,天津市300060 [5]天津医科大学附属肿瘤医院泌尿肿瘤科,天津市300060

出　　处：《中国肿瘤临床》2013年第12期733-735,740,共4页Chinese Journal of Clinical Oncology

摘　　要：髓系肉瘤是一种少见的血液系统恶性肿瘤,常伴随急性髓系白血病(AML)或作为AML复发时的首要表现。本科2010年11月收治1例患者以睾丸髓系肉瘤起病,1个月后进展为标准的AML。该患者接受异基因干细胞移植后骨髓达完全缓解,但移植后5个月出现右肾上腺占位。综合了影像科、PET-CT室、放疗科、泌尿肿瘤科的诊治意见,给该患者行右肾上腺射波刀放疗。随访至2013年3月,该患者无论骨髓还是髓外均未再发现病灶。Myeloid sarcoma is a rare hematological neoplasm that may develop de novo or concurrently with acute myeloid leukemia （AML）, or represent the initial manifestation of relapse in a previously treated AML in remission. A 44-year-old man was diagnosed with testis MS in his local hospital. A month later, November 2010, our department confirmed the clinical diagnosis of AML through his bone marrow biopsy and aspirate. The patient underwent allogeneic hematological stem cell transplantation from his sister and achieved complete remission. Five months later, however, a mass in his adrenal was revealed by Positron Emission Tomogra- phy-Computer Tomography （PET-CT）. After a multidisciplinary team diagnosis, radiotherapy for this lesion was performed. As of the follow up conducted until March 2013, the patient remains healthy and shows no evidence of recurrent MS or leukemia.

关 键 词：髓系肉瘤 急性髓系白血病 异基因干细胞移植 多学科诊疗模式 

分 类 号：R733[医药卫生—肿瘤]