35例舌下腺肿瘤临床治疗分析  

Diagnosis and Treatment of Sublingual Gland tumors:Clinical Analysis of 35 Cases

作　　者：李田[1,2,3] 孙国文[1,2,3] 卢明星[1,2,3] 杨旭东[1,2,3] 王志勇[1,2,3] 胡勤刚[1,2,3] 唐恩溢[1,2,3] 

机构地区：[1]南京大学医学院口腔医学院 [2]南京大学医学院附属口腔医院 [3]南京市口腔医院口腔颌面外科,江苏南京210008

出　　处：《口腔医学研究》2013年第6期554-556,共3页Journal of Oral Science Research

基　　金：江苏省自然科学基金课题项目(编号:BK2011102);江苏省临床医学专项(编号:BL2012017)

摘　　要：目的:探讨舌下腺肿瘤的发病情况、病理特征及治疗方法。方法:对1998～2011年南京大学附属口腔医院收治的35例舌下腺肿瘤病例临床资料进行回顾性分析。结果:35例舌下腺肿瘤患者中,男性10例,女性25例,男女比例1∶2.5;年龄19～71岁,平均48.8岁,恶性肿瘤28例,占80.0%,其中腺样囊性癌是主要的病理类型,有22例;良性肿瘤7例,占20.0%。恶性肿瘤患者中有23例行颈淋巴结清扫术,占82.1%。而舌下腺良性肿瘤患者,均采取局部切除肿瘤及舌下腺。结论:舌下腺肿瘤女性发病率高于男性;好发年龄为48.8岁;腺样囊性癌和粘液表皮样癌是舌下腺常见的恶性肿瘤,多形性腺瘤是常见的良性肿瘤;对于舌下腺恶性肿瘤患者,早期诊断、扩大切除及相应的颈淋巴结清扫术是改善预后的关键。对于舌下腺良性肿瘤,将肿瘤及舌下腺完整切除是足够的。Objective： To retrospectively assess the morbidity, pathological features and therapeutic efficacy of sublingual salivary gland tumors. Methods： A total of 35 hospitalized cases of sublingual gland tumors which were obtained from School of Stomatology, Nanjing University Medical Center, Nanjing University,Stomatological Hos- pital of Nanjing from 1998--2011. Results： There were 35 patients of sublingual gland tumors, 10 males, 25 fe- males,the ratio of males to females was 1..2.5;aged 19 to 71 years,the mean age was 48.8 years. 28 cases were ma- lignant sublingual gland tumours （80.0%） and of these, 22 were adenoid cystic carcinoma. Adenoid cystic carcino- ma was mainly of the histological type. 7 cases were benign tumours （20. 0%）. For malignant sublingual gland tumours, 23 patients underwent neck dissection（82. 1%）. The resection of the tumour and sublingual gland was performed in the benign sublingual gland tumours. Conclusion： The incidence of female is higher than male. Ade noid cystic carcinoma and mucoepidermoid carcinoma are the most common type of malignant sublingual salivary gland tumors. Pleomorphic adenoma is the most common type of benign sublingual gland tumours. For malignant sublingual gland tumours, early diagnosis and extended resection and appropriate neck dissection is the key to im- proving prognosis. For benign sublingual gland tumours, the resection of tumour and sublingual gland is the pre- ferred treatment.

关 键 词：舌下腺 肿瘤 临床分析 

分 类 号：R739.87[医药卫生—肿瘤]