孤立性纤维性肿瘤影像表现及病理对照分析  

Solitary fibrous tumors:imaging diagnosis and clinical pathological correlation

作　　者：侯刚强[1] 张小静[2] 沈比先[1] 熊伟[3] 

机构地区：[1]广东医学院附属南山医院放射科,广东深圳518052 [2]深圳大学医学院,广东深圳518060 [3]南方医科大学南方医院影像中心,广东广州510515

出　　处：《医学影像学杂志》2013年第6期894-898,共5页Journal of Medical Imaging

摘　　要：目的探讨孤立性纤维性肿瘤(SFT)的影像表现及病理特点。方法分析23例SFT影像资料,并与病理及免疫组化对照研究。结果 20例患者表现为孤立、界清的圆形或卵圆形软组织肿块,3例患者呈囊实性。增强扫描实性部分明显强化,延迟扫描进一步强化。肿瘤T1WI、T2WI像呈低信号。病理表现为梭形细胞与胶原混杂排列;4例肿瘤细胞异型性明显,异常核分裂像增多。免疫组化CD34、Vimentin阳性。结论 SFT可发生于机体多个部位,具有较特异的影像表现,定性需靠病理及免疫组织化学检查。Objective We aimed to analyze the computed tomography （CT）, magnetic resonce imaging （MRI） and pathological findings of solitary fibrous tumors （SFT）. Methods CT, MRI and pathology images of 23 patients with SFT con firmed by pathology were retrospecively reviewed, and a comparison with histopathological and immunohistochemieal re- sults were made. Results 20 cases showed solitary oval or rouned well-defined masses, and 3 cases showed cystic solid masses. Contrast-enhanced images showed marked, heterogeneous enhancement, and delayed enhancement. On T1 WI and T2WI, most tumors were hypointensive. The pathological features of SFT contained mixed various amount of spindle cells and collagen, with CD34 and Vimentin being immunohistochemical positivity. Four cases of malignant solitary fibrous tumors demonstrated cytological atypia obviously and tumor necrosis. Conclusion SFT can be seen in multi-parts of the body, and can demonstrate characteristic CT and MRI features, which is helpful for the diagnosis, yet final diagnosis should be based on histopathology and immunohistochemistry examinations.

关 键 词：孤立性纤维性肿瘤 体层摄影术 X线计算机 磁共振成像 免疫组织化学 

分 类 号：R734[医药卫生—肿瘤] R445[医药卫生—临床医学]