采用双能量CT碘定量法研究正常活体肝脏的肝动脉和门静脉血供特点  

Quantitative study of dual-perfusion characteristic of liver on normal living bodies by dual-energy CT

作　　者：谢婷婷[1] 王成林[1] 丁贺宇[1] 黎永滨[1] 

机构地区：[1]北京大学深圳医院放射科,518000

出　　处：《中华放射学杂志》2013年第6期526-528,共3页Chinese Journal of Radiology

摘　　要：目的应用双能量cT碘定量的方法，探讨正常活体肝脏左、有叶及尾状叶的肝动脉和门静脉双重血流灌注量（或碘含量）的生理特点。方法对77例行上腹部cT检查肝脏正常的患者行上腹部双能量CT增强扫描，选择规定的ROI测定碘含量，应用双能量分析软件对比研究增强后动脉期、门静脉期肝左、右叶及尾状叶的碘定量，并对肝左右叶及尾状叶的碘含量、肝动脉期／门静脉期血流量比值进行方差分析比较。结果肝尾状叶肝动脉期碘含量为（851±35）μg／L、门静脉期碘含量为（2912±78）μg/L，肝左叶肝动脉、门静脉期碘含量分别为（445±34）和（2373±77）μg/L，肝右叶肝动脉、门静脉平均碘含量分别为（504±30）和（2515±78）μg/L，尾状叶与肝左、肝右叶差异均有统计学意义（P值均〈0．05）。肝左叶、肝有叶和尾状叶肝动脉／门静脉血流量比值分别为（28．41±3．42）％、（35．76±5．80）％和（49．92±4．63）％，差异有统计学意义（F=5．36，P〈0．01）。结论双能量CT物质分离功能和碘定量可用于反映肝脏各叶双重血供情况。正常人肝尾状叶的肝动脉、门静脉血流量与肝左、右叶存在明显差异。objective Using iodimetric analysis of dual-energy CT, to explore the dual perfusion amount and proportion of hepatic artery and portal vein in different hepatic lobes on normal living bodies. Methods A total of 77 patients without hepatic diseases underwent contrast-enhanced upper abdomen dual-energy CT scanning. The raw data were transferred to the workstation for postprocessing. ROI were selected, then the iodine content in arterial phase, portal phase and delay phase were calculated automatically. The differences of these measures （ iodine content and hepatic artery to portal vein perfusion ratio of the left hepatic lobe, right hepatic lobe and caudate lobe） in the left, right and caudate lobe of liver were detected by using ANOVA test. Results The iodine concentration in the caudate lobe was （851 ± 35 ）μg/L from hepatic artery and （2912 ± 78 ） μg/L from portal vein. The iodine concentration in the left hepatic lobe was （ 445 ± 34 ） μg/L from hepatic artery and （ 2373 ± 77 ）μg/L from portal vein. The iodine concentration in the right hepatic lobe was （504 ± 30 ） μg/L from hepatic artery and （2515 ± 78 ）μg/L from portal vein. The perfusion condition （ amount of blood supply） of caudate lobe showed a significant statistic difference from the left and right hepatic lobe（P 〈0. 05） ,and the amount of blood supply from both sources were more than those of the left and right hepatic lobes. There was no significant statistic difference in the amount of hepatic artery and portal vein blood supply between the right and left hepatic lobe（ P 〉 0.05 ）. The proportions of blood supply from hepatic artery and portal vein （ hepatic artery/portal vein） were different among the three hepatic lobes, which was （28.41 ± 3.42） % in left lobe, （ 35.76 ± 5.80） % in right lobe and （49.92 ±4.63）% in caudate lobe, respectively（ F =5.36,P 〈0. 01）. Conclusion Dual-energy CT can be used to study the dual-pcrfusion condition of the liver. On normal living bodi

关 键 词：肝脏 体层摄影术 X线计算机 能谱成像 

分 类 号：R735.7[医药卫生—肿瘤]