超声造影对子宫内膜癌分期的应用价值  

Application value of contrast-enhanced ultrasound for stage of endometrial carcinoma

作　　者：丁燕[1,2] 郭钰珍[1] 管玲[2] 王海燕[1] 张栋栋[1] 王雨村[2] 

机构地区：[1]兰州大学第二医院妇产科,兰州730030 [2]甘肃省肿瘤医院妇瘤科,兰州730050

出　　处：《重庆医学》2013年第18期2103-2106,共4页Chongqing medicine

摘　　要：目的探讨超声造影(CEUS)对子宫内膜癌分期的参考价值。方法回顾性分析40例经病理检查证实为子宫内膜癌患者的CEUS表现、肌层浸润深度及宫颈受累情况,并与术后病理分期进行对照。结果 CEUS诊断子宫内膜癌Ⅰa期的敏感度、特异度、准确率、阳性预测值及阴性预测值分别为94.12%(16/17)、82.61%(19/23)、87.50%(35/40)、80.00%(16/20)、95.00%(19/20);Ⅰb期的敏感度、特异度、准确率、阳性预测值及阴性预测值分别为82.35%(14/17)、95.65%(22/23)、90.00%(36/40)、93.33%(14/15)、88.00%(22/25);Ⅱ期的敏感度、特异度、准确率、阳性预测值及阴性预测值分别为80.00%(4/5)、97.14%(34/35)、95.00%(38/40)、80.00%(4/5)、97.14%(34/35)。CEUS示Ⅰa期20例,Ⅰb期15例,Ⅱ期5例,与手术记录及病理检查结果相一致。结论 CEUS在判断Ⅰ、Ⅱ期子宫内膜癌肌层及宫颈浸润情况及术前分期中有较高临床应用价值。Objective To explore the reference value of CEUS in stage of endometrial carcinoma.Methods CEUS features of stage of endometrial carcinoma proved by operation and pathology in 40 patients were analyzed retrospectively.CEUS diagnosis of myometrial and cervical invasion were compared with the results of pathologic examine.Results Compared with postoperative pathology results,the sensitivity,specificity,accuracy,positive predictive value and negative predictive value of CEUS assessment for tumors confined to stage Ia was 94.12%（16/17）,82.61%（19/23）,87.50%（35/40）,80.00%（16/20）,95.00%（19/20）,stage I b was 82.35%（14/17）,95.65%（22/23）,90.00%（36/40）,93.33%（14/15）,88.00%（22/25）,stage Ⅱ was 80.00%（4/5）,97.14%（34/35）,95.00%（38/40）,80.00%（4/5）,97.14%（34/35）,respectively.The tumors were divided into stage I a（n=20）,stage Ib（n=15）and stage Ⅱ（n=5）with CEUS.Conclusion CEUS has considerable value of clinical application in judging the myometrial and cerxical invasion and local-regional staging of stage I and Ⅱ endometrial carcinoma.

关 键 词：子宫内膜肿瘤 肿瘤分期 超声造影 

分 类 号：R737.33[医药卫生—肿瘤]