计算机辅助技术对血管性痴呆患者的认知康复的疗效观察  

The Efficacy of Computer Assisted Cognitive Training on Cognitive Rehabilitation in Vascular Dementia Patients

作　　者：陈晓飞[1] 倪姣娜[2] 林阁[2] 

机构地区：[1]浙江中医药大学,310053 [2]浙江医院,310013

出　　处：《心脑血管病防治》2013年第3期196-199,共4页CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT

摘　　要：目的观察计算机辅助技术对血管性痴呆(vascular dementia,VD)患者的认知康复的疗效。方法将38例符合纳入标准的VD患者随机分为对照组和训练组,每组19例患者。对照组和训练组均给予规范抗痴呆药物治疗、常规康复训练。训练组在此基础上接受计算机辅助认知康复训练,1次/天,30分/次,治疗8周。分别于训练前、训练8周后采用简易精神状态量表(Mini-metal State Examination,MMSE)、蒙特利尔认知评估量表中文版(Montreal cognitive assessment,MoCA)对两组患者进行认知功能评定。比较训练组和对照组治疗前后的组内及组间成绩。结果计算机训练组及对照组MMSE、MoCA总分均比训练前提高(P<0.05);计算机训练组成绩高于对照组(P<0.01);轻、中度VD患者成绩提高明显(P<0.05),重度VD患者成绩提高无统计学差异(P>0.05)。结论规范的抗痴呆药物治疗可以改善VD的认知功能;药物联合计算机辅助技术训练,改善VD认知功能更显著;认知康复训练对改善轻、中度VD患者的认知功能效果显著,对重度VD患者疗效欠佳。Objective To investigate the efficacy of computer assisted cognitive training on cognitive rehabilitation in patients with vascular dementia （VD）. Methods 38 patients of Zhejiang Hospital with vascular dementia were randomly divided into two groups： cognitive training group and control group. Each group have 19 patients . The general data of each group showed no significant differ- ence. The control group and the training group were given the same specification anti-dementia drug treatment, conventional rehabili- tation. At the same time, The traning group accept computer-assisted cognitive rehabilitation： 1/day, 30m-in/time, 8weeks of treat- ment. Respectively, before and after eight weeks of training, using the Mini-metal State Examination（MMSE） and the Montreal cogni- tive assessment（MoCA） assessed the cognitive function of the two groups. Compare the training and control groups before and after treatment group and between-group results. Results At the beginning, the MMSE scores and the MoCA scores in beth groups had no significant differences （ P 〉 0.05）. At the eighth week, the MMSE scores and the MoCA scores were improved in beth groups （ P 〈 0.05） , especially in the training group （ P 〈 0.01）. The scores of the mild to moderate VD patients is improved significantly （ P 〈 0.05）. The scores in patients with severe VD is also increased, but has no significant difference （ P 〉 0.05）. Conclusions The com- puter-assisted cognitive training can significantly improve the cognitive function of patients with VD. This study is to improve and pro- mote the set of cognitive training software that can provide a good help, and for cognitive software widely used to provide good clinical experience. Cognitive rehabilitation training significantly improved the cognitive function in patients with mild to moderate VD, but had poor efficacy on patients with severe VD.

关 键 词：痴呆 血管性痴呆 计算机辅助认知康复训练 认知功能评定 

分 类 号：R749.13[医药卫生—神经病学与精神病学]