改良Ferriman-Gallwey评分系统用于广东省育龄期汉族妇女体毛评价的分析  

Study on the facial and body terminal hair growth in women in Guangdong by using modified Ferriman-Gallwey scoring system

作　　者：赵晓苗[1] 倪仁敏[1] 黄佳[1] 黄丽丽[1] 杜尚明[2] 马梦君[2] 林淡钰[2] 杨冬梓[1] 

机构地区：[1]中山大学孙逸仙纪念医院妇产科,广州510120 [2]中山医学院临床医学系

出　　处：《中华妇产科杂志》2013年第6期427-431,共5页Chinese Journal of Obstetrics and Gynecology

摘　　要：【摘要】目的了解广东省育龄期汉族妇女体毛生长状况，探讨年龄、月经紊乱以及多囊卵巢对终毛生长状况的影响，并提出改良Ferriman—Gallwey（mFG）评分系统对多毛症的评分诊断界值。方法2008年6月至2009年7月采用四级系统随机抽样的方法，抽取广东省两个城市和两个农村共16个社区的育龄期（20～45岁）妇女2988例，采用mFG评分系统对体毛分布进行评价，并用K一聚类分析法计算多毛症的诊断界值。按照不同的年龄分组（20一岁组982例、26一岁组765例、31～岁组597例、36～岁组384例、41—45岁组260例）；因部分数据记录错误或缺失，导致部分病例从组别中删除，最终根据有、无月经紊乱，有、无多囊卵巢分为月经紊乱组488例、月经正常组2413例，多囊卵巢组568例、非多囊卵巢组2207例，比较各组多毛症mFG评分系统诊断界值，以及各组多毛症妇女痤疮、月经紊乱、黑棘皮症和多囊卵巢的发生率。结果（1）在2988例妇女中，mFG评分系统〉／7分149例（5．0％），／〉5分314例（10．5％），／〉2分747例（25．0％）。（2）在总人群中，多毛症mFG评分系统诊断界值为≥5分；月经紊乱组和多囊卵巢组mFG评分系统评分第90、95百分位数均分别低于月经正常组、非多囊卵巢组（P均〈0．05）。（3）年龄分组结果显示：mFG评分系统相应百分位数和多毛症诊断界值均随着年龄增加而下降（P〈0．05）；多毛症mFG评分系统诊断界值在20一岁组为≥6分，26～岁组为≥5分，而31～岁组、36～岁组、41—45岁组则均为I〉4分。（4）总人群中多毛症妇女痤疮、月经紊乱、多囊卵巢发生率分别为45．5％（143／314）、73．6％（231／314）、25．8％（81／314），正常毛发妇女分别为25．1％（671／2674）、16．1％（431／2674）、19．8％（529／2674），两者分别比较，差异均有统计学意义（P〈0�Objective To study growth of facial and body terminal hair of women in Guangdong province and its relationship with age, menstrual irregularities and polycystic ovary, and determine normative cut-off score of modified Ferriman and Gallwey （mFG）. Methods A cross-sectional study was conducted on 2988 women at age of 20-45 years from 16 communities of two urban and two rural regions in Guangdong province from June 2008 to July 2009. Terminal body hair growth was assessed by using the modified Ferriman and Gallwey （mFG） scoring system. The normative cut-off value of mFG were calculated by using the K-means cluster analysis （ K = 2 ）. Those women were classified into following groups, including 982 women at group of ages of 20- years, 765 women at group of 26- years, 597 women at group of 31- years, 384 women at group of 36- years, 260 women at group of 4145 years. Due to absence or errors of medical records, some cases were excluded from this study. Based on menses irregularities （MI）, polycystic ovaries （PCO） , there were 488 cases in MI group, 2413 cases in normal menses group, 568 cases in PCO group, and 2207 cases in non-PCO group finally. The incidences of acne, MI, acanthosis nigricans, and polycystic ovaries were also analyzed in all the hirsute groups. Results （ 1 ） among 2988 women, it was observed 149 women （5%） with mFG I〉7, 314 women （10. 5% ） with I〉 5, 747 women with mFG〉2. （2） Cluster analysis identified an mFG score of 5 as the cut-off value that define abnormal hirsute in the total population and all the sub-groups with/without MI or PCO ; （ 3 ） Based on age classification, it was found that increased age was associated with decreased trends of the percentile and cut-off value of hirsutism. The value of hirsutism of mFG were 6 in group of 20- years, 5 in group of 26- years, 4 in groups of 31- years, 36- years and 4145 years. （4） The prevalence of aene, menstrual irregularities and POC were 45.5% （143/314） , 73.6% （ 231/314 ）, 25.8% （ 81/314

关 键 词：多毛症 多囊卵巢综合征 毛发 横断面研究 聚类分析 试验预期值 疾病严重程度指数 汉族 

分 类 号：R711.75[医药卫生—妇产科学]