种植体周围龈沟液中硫离子含量的测定及其临床意义  

Determination of Sulfide Levels in Gingival Crevicular Fluid around Dental Implants and Its Clinical Significance

作　　者：李明[1] 逄爱慧[1] 杨焰[1] 吴丽娟[1] 马净植[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院口腔医学中心,武汉430030

出　　处：《华中科技大学学报（医学版）》2013年第3期311-313,共3页Acta Medicinae Universitatis Scientiae et Technologiae Huazhong

摘　　要：目的分析种植体周围龈沟液(gingival crevicular fluid,GCF)中硫化物水平(sulfide levels,SUL)与种植体牙周指数之间的相关性,探讨SUL作为种植体牙周监测指标的可行性。方法设种植体周围黏膜炎组(peri-implant mu-cositis,PIM)47例(47颗牙位);种植体周围炎组(peri-implantitis,PI)26例(26颗牙位)和健康种植牙对照组50例(50颗牙位)。每个牙位记录6个位点,采用金刚牙周诊断仪测量所选位点GCF中SUL和种植体牙周临床指标:龈沟出血指数(sulcus bleeding index,SBI)、探诊深度(probing depth,PD)、附着丧失(attachment loss,AL)。检查并记录菌斑指数(plaque index,PLI)。各组数据采用SPSS 12.0进行统计学分析。结果 SUL在PI组(0.355 9±0.039 0)pg/mL、PIM组(0.125 3±0.037 1)pg/mL和对照组(0.052 8±0.017 3)pg/mL中存在统计学差异(P<0.01),且随着种植体周围组织病变程度的加重而上升;SUL与种植体牙周临床指标:PLI(r=0.733)、SBI(r=0.859)、PD(r=0.873)、AL(r=0.606)呈正相关(P<0.01)。结论种植体周围GCF中SUL与种植体牙周临床指标之间存在相关关系,其水平的高低变化可客观反映种植体周围组织的健康状态和病变进展。Objective To evaluate the correlation between sulfide level in gingival crevicular fluid around dental implants and the peri-implant parameters,and to explore the feasibility of using SUL as a peri-implant monitoring index.Methods Three groups were designed,including peri-implant mucositis（PIM）group（47 implants）,peri-implantitis（PI）group（26 implants） and normal control group（50 implants）.Six sites were randomly selected around the dental implants.The sulfide level in the gingival crevicular fluid at the selected sites was measured by using Diamond Probe/Perio 2000 System as well as the peri-implant clinical parameters such as sulcus bleeding index（SBI）,probing pocket depth（PD）and attachment loss（AL）.Results There were significant differences in the sulfide level among the three groups[（0.355 9±0.039 0）pg/mL in PI group,（0.125 3± 0.037 1）pg/mL in PIM group,（0.052 8±0.017 3）pg/mL in control group]（P〈0.01）.The sulfide level was increased with the severity of the peri-implant lesion.It was positively correlated with such peri-implant parameters as PLI（r=0.733）,SBI（r=0.859）,PD（r=0.873）and AL（r=0.606）（P〈0.01）.Conclusion The sulfide level in the gingival crevicular fluid around dental implants was significantly correlated with the clinical peri-implant indices,suggesting that the sulfide level may be used to reflect the status of peri-implant tissues and the lesion progression in clinical practice.

关 键 词：硫化物 龈沟液 种植体周围炎 

分 类 号：R781.4[医药卫生—口腔医学]