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机构地区:[1]襄阳职业技术学院附属医院,湖北襄阳441021 [2]襄阳市中心医院,湖北襄阳441021
出 处:《中国肿瘤》2013年第6期477-480,共4页China Cancer
摘 要:[目的]探讨甲状腺结节合并钙化与甲状腺癌的关系。[方法]回顾性分析2007年1月至2012年11月197例甲状腺患者的彩色超声资料与病理诊断结果。[结果]197例甲状腺结节中,钙化率为41.6%(82/197),其中甲状腺良性疾病中钙化率为21.4%(27/126),而在甲状腺癌中钙化率达77.5%(55/71)(X2=58.684,19〈0.001)。钙化诊断甲状腺癌的ROC曲线下面积为0.780(95%CI:0.710~0.850),其中微钙化ROC曲线下面积为0.748(95%CI:0.672~0.823),粗钙化ROC曲线下面积为0.625(95%CI:0.540~0.710)。『结论]钙化尤其是微钙化对于甲状腺癌的诊断价值较高。[Purpose] To investigate the relationship between thyroid nodule with calcification and thyroid carcinoma. [Methods] The uhrasonagraphy and pathological data of 197 patient with thyroid carcinoma from January,2007 to November,2012 were retrospectively analyzed. [Results] Among 197 patients,the rate of calcification in thyroid nodule was 41.6% (82/197). The rate of calcification in thyroid carcinoma was 77.5% (55/71 ), and 21.4% (27/126) in benign thyroid nodule(x2=58.684, P〈 0.001). The area of ROC curve of calcification for diagnosis of thyroid carcinoma was 0.780(95%CI: 0.710-0.850),while the area of ROC curve of rnicrocalcification was 0.748 (95%C1:0.672-0.823), and macrocalcification was 0.625 (95%CI : 0.540-0.710). [ Conclusions I Presence of calcification in thyroid nodule, especially microealcification is valuable for the diagnosis of thyroid carcinoma.
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