胃癌全胃切除术后消化道重建方式的研究现状  

Current Status of Digestive Tract Reconstruction in Total Gastrectomy for Gastric Cancer

作　　者：陈健[1] 陈心足[1] 胡建昆[1] 

机构地区：[1]四川大学华西医院胃肠外科中心,四川成都610041

出　　处：《中国普外基础与临床杂志》2013年第6期604-607,共4页Chinese Journal of Bases and Clinics In General Surgery

基　　金：国家自然科学基金(项目编号:81071777);国家教育部新世纪优秀人才支持计划(项目编号:2012SCU-NCET-110343);中央高校基本科研业务费专项资金;四川大学优秀青年学者科研基金(项目编号:2011SCU04B19)~~

摘　　要：目的总结胃癌全胃切除术后消化道重建方式的研究进展。方法复习近年来国内外关于全胃切除术后消化道重建方式的研究并作综述。结果胃癌患者全胃切除术后的生活质量越来越受到重视,消化道重建方式对胃癌患者术后的生活质量有最直接的影响。全胃切除术后的食物储袋构建和保持肠管神经肌肉连续性在消化道重建中具有一定的临床意义。目前认为,储袋重建安全、有效,可改善胃癌患者术后的生活质量;而保留十二指肠通道的重建方式并没有明显的优势。结论全胃切除术后的消化道重建仍有许多问题需要研究解决,有待于更深入的基础研究及更高质量的临床研究。Objective To summarize the research progress of digestive tract reconstruction after total gastrectomy in gastric cancer.Methods The domestic and international published literatures about digestive tract reconstruction after total gastrectomy in gastric cancer were retrieved and reviewed.Results More and more attention had been paid to the postoperative quality of life after total gastrectomy in gastric cancer,and the most related factor for postoperative quality of life was the type of digestive tract reconstruction.The pouch reconstruction and preservation of enteric myoneural continuity showed beneficial effects on clinical outcomes.Current opinion considered the pouch reconstruction might be safe and effective,and was able to improve the postoperative quality of life of patients with gastric cancer.However,the preservation of duodenal pathway didn’t show significant benefits.Conclusion The optimal digestive tract reconstruction after total gastrectomy is still debating,in order to resolve the controversies,needs more in-depth fundamental researches and more high-quality randomized controlled trials

关 键 词：胃癌 全胃切除术 消化道重建 

分 类 号：R735.2[医药卫生—肿瘤]