食管癌行为生活方式危险因素病例对照研究  

Case-control study of behavior and lifestyle risk factors for esophageal cancer

作　　者：韩建英[1] 王民宪[1] 李笑梅[1] 邢海平[1] 乔永青[1] 徐致祥[2] 

机构地区：[1]河南省安阳市疾病预防控制中心,河南安阳455000 [2]广东省佛山市第一人民医院,广东佛山528000

出　　处：《国外医学（医学地理分册）》2013年第2期89-92,共4页Foreign Medical Sciences：Section of Medgeography

基　　金：国家高技术研究发展计划(863计划)项目(No.2009AA02Z421)

摘　　要：目的食管癌行为生活方式危险因素病例对照研究,为食管癌病因预防提供理论依据。方法统一制定调查表对全市2008年末531人食管癌新发病例,90岁以上老人4 287人进行调查。结果病例和对照均以农民职业为主,分别为92.22%、92.82%。在这些农民职业人群中,有文化、教师、医生、业余时间看电视、看报、读书、喜音乐、不参加社交活动、喜散步、烹调、做家务、看孩子、搓麻将、有存款、有退休金等病例组显著高于对照组;在婚、夫妻独居生活、男性显著高于对照组;喜荤腥、吃猪肉、盐味重、喝奶、吸烟、睡眠差显著高于对照组;长期居住在山区、丘陵、洼地、地区缺水、饮用水源在山顶、在山腰、在谷底、在河边、在低洼处、居民饮用山泉水、河边井水、河渠窖库水、患其他慢性病及家族患慢性病比率显著高于对照组。结论水污染、过度疲劳、营养不良、吸烟、不良情绪有害健康易患肿瘤,人群饮用水污染是安阳食管癌高发区产生的一个主要因素。Objective Case-control study is conducted to analyze the behavior and lifestyle risk factors for esophageal cancer in to provide a theoretical basis for etiology prevention of esophageal cancer. Methods A unified questionnaire was designed to investigate 531 new esophageal cancer cases and 4 287 people over 90 years old in the whole city by the end 2008. Results By the end 2008 the the cases group had 531, of which 330 were male and accounted for 62.15%, and 201 were women and accounted for 37.85% ; the control group had 4 287 people, 728 males accounted for 22.23%, female 2 547, 77.77% . In cases group, these indexes were significantly higher than those in the control group, including professions as intellectuals, teachers, doctors; part-time entertainments such as watching television, reading newspapers and books, listening to music; unsociable, fond of walking, cooking, doing housework, babysitting, playing mahjong; having deposits and retirement; The index for males in lifestyle such as married or single was significantly higher than that in the control group; In diet these norms were significantly higher than those in the control group, such as apt to meat, salty flavor, milk, smoking, poor sleep; In dwelling environment, these indexes were significantly higher than those in the control group, such as permanent residence in the mountains, hills and low lands, water-stressed areas, the source of drinking water on mountaintop or slides, at valley floor, by riverside and in low-lands, residents drinking mountain springs, wells by river banks, canals, the reservoir cellar water. In cases group, the ratio of suffering from other chronic diseases in themselves and family chronic diseases was significantly higher than that in the control group. Conclusion These risk factors such as water pollution, fatigue, malnutrition, dysthymia, smoking, are harmful to the health and susceptible to tumor. Drinking water pollution is a maior factor for the high esoohageal cancer in Anvang.

关 键 词：食管癌 行为生活方式 危险因素 病例对照研究 

分 类 号：R735[医药卫生—肿瘤]