MatriXX两种调强放疗剂量验证方法的比较分析  

Analyse two kinds of intensity-modulated radiotherapy verification methods comparatively by using the MatriXX

作　　者：戴越[1] 胡春红[2] 李小东[1] 郭妍妍[1] 

机构地区：[1]天津医科大学第二医院放疗科,300211 [2]天津医科大学生物医学工程学院,300070

出　　处：《中华放射肿瘤学杂志》2013年第4期312-314,共3页Chinese Journal of Radiation Oncology

摘　　要：目的对MatriXX进行调强放疗剂量验证所用机架角归零和实际机架角方法进行比较，分析两种方法得出的多角度合成通过率是否存在差异。方法对12例头颈部肿瘤患者的调强放疗剂量分别用上述两种方式进行验证，以3mm3％标准进行γ通过率分析。对不同机架角下两种方式验证结果行配对t检验，对多野合成的两种方式验证结果行单因素方差分析。结果使用实际角度方法的γ通过率比角度归零方法普遍有所下降，但80°、120°、240°时最明显，分别为98．71％与93．59％（t=2．10，P=0．000）、98．15％与93．17％（t=2．10，P=0．000）、98．94％与92．85％（t=2．10，P=0．000）。多野合成的两种方式验证结果相似98．27％与94．63％（F=0．50，P=0．134）。结论两种调强放疗剂量验证方式从两个不同立场进行，对其结论进行比较分析可更全面保障调强放疗计划验证的准确性。Objective To explore the MatriXX measurements the dose distributions for each beam in intensity-modulated radiotherapy （ IMRT ） plans were measured with 0 degree gantry angle and actual gantry position respectively. To discuss whether the two multi-angle synthetic pass rate from the two methods has statistics differences. Methods The dose distributions for each beam in IMRT plans were measured with 0 degree gantry angle and actual gantry position for twelve patients with head and neck tumor respectively. The γ pass rates （according to 3%/3 mm） for each beam under each angle condition was obtained by the comparison between the measured and the calculated dose distributions from the treatment planning system which was treated as the reference distribution. Use the t-test to analyse the actual gantry angle method and use the one factor analysis of variance to analyze the two multi-angle synthetic pass rate from the two methods. Results The γ pass rates of actual gantry angle was found generally declined seemingly compared with 0 degree gantry angle, but different γ pass rates showed only in 80°, 120° and 240° with 98. 71%, 93.59%（t=2.10,P=0.000）,98.15%,93.17% （t=2.10,P=0.000） and 98. 94%, 92. 85% （t = 2. 10 ,P = 0. 000） respectively. The γ pass rate of multi-angle synthetic was seemingly between methods （98. 27% ,94. 63% , F = 0. 50, P = 0. 134 ）. Conclusions Two kinds of IMRT verification mode are from two position to validated the IMRT plans dose accuracy, comparatively analysing the conclusions drawn from the two methods can protect accuracy of IMRT plans more comprehensively.

关 键 词：MatriXX电离室矩阵 剂量验证 调强放疗 

分 类 号：R739.91[医药卫生—肿瘤]