药物辅助康复训练对脑瘫患儿的疗效观察  

Evaluation of the curative effect of medication together with rehabilitation training on cerebral palsy children

作　　者：管恩本[1] 辛杰 郭慧玲[3] 李洁[4] 徐琳[5] 

机构地区：[1]青岛大学医学院附属医院黄岛院区儿科,山东青岛266500 [2]日照市中医院,山东日照276800 [3]青岛大学医学院附属医院,山东青岛266500 [4]日照市人民医院儿科,山东日照276800 [5]青岛大学医学院附属医院黄岛院区神经内科,山东青岛266500

出　　处：《华夏医学》2013年第3期467-469,共3页Acta Medicinae Sinica

摘　　要：目的:比较神经节苷脂(GM1)、施普善、神经生长因子(NGF)单用及联合应用对脑瘫患儿的疗效。方法:患儿共分为6个组。A组:康复训练组;B组:康复训练加GM1;C组:康复训练加施普善;D组:康复训练加GM1和NGF;E组:康复训练加施普善和NGF;F组:康复训练加NGF。10d为1个疗程,共6个疗程。采用Gesell发育量表测评治疗前后患儿发育商,比较疗效差异。结果:药物治疗组与单纯康复组比,疗效有差异;药物治疗组之间比较,GM1和NGF联合疗效最好。结论:康复治疗联合使用GM1与NGF对于脑瘫患儿疗效最好。Objective： To evaluate the curative effect of ganglioside GM1, cerebrolysin and nerve growth factor （NGF） combined with rehabilitation training on the cerebral palsy children. Methods： The patients were devided into six groups. Group A were given rehabilitation training only; Group B received GMI and rehabilitation training; Group C received rehabilitation training together with cerebrolysin; Group D underwent rehabilitation training added with GM1 and NGF; Group E conducted rehabilitation training together with cerebrolysin and NGF; and Group F underwent rehabilitation training together with NGF. All patients received six courses of treatment （10 days as a course of treatment）. The development quotients （DQ） of patients before and after the treatment were compared and evaluated with Gesell. Results： Medication conbined with rehabilitation training in the treatment of cerebral palsy children was much better than the single rehabilitation training, while GM1 and NGF used together could gain the best results. Conclusion. Combined use of GM1 and NGF together with rehabilitation training had the best effect on the cerebral palsy children.

关 键 词：神经节苷脂 施普善 神经生长因子 脑性瘫痪 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R453[医药卫生—临床医学]