波前像差引导的准分子激光屈光手术像差研究  

A clinical study between coneal wavefront aberration guided LASIK and LASEK on higher order aberration

作　　者：张幼梅[1] 

机构地区：[1]郑州大学第一附属医院眼科,450052

出　　处：《中华眼外伤职业眼病杂志》2013年第7期489-492,共4页Chinese Journal of Ocular Trauma and Occupational Eye Disease

摘　　要：目的分析波前像差引导的准分子激光原位角膜磨镶术（LASIK）和准分子激光角膜上皮瓣下磨镶术（LASEK）对近视眼高阶像差的影响，并作对比观察分析。方法角膜波前像差引导矫治近视61例（122眼）。其中LASIK（A组）27例（54眼），LASEK（B组）34例（68眼），分别于术前和术后7d、1个月、3个月测量高阶像差，并分析手术前后高阶像差的变化和两种手术方式对高阶像差产生的影响。结果两组术后总高阶像差均方根值均较术前有所增加（P〈0．05），以三阶、四阶像差增加为主，五阶、六阶像差则较术前变化不明显，术后B组的总高阶像差、三阶、四阶像差均小于A组（P〈0．05）。两组的慧差和球差均比术前有所增加（P〈0．05），其中A组的垂直慧差较B组增高明显，两组间差异有统计学意义（P〈0．05）。结论角膜波前像差引导的LASIK和LASEK术后都会使术眼高阶像差有不同程度的增加，总体来讲，LASEK的增加幅度小于LASIK。Objective To analyze the effects of coneal wavefront aberration guided laser in situ keratomileusis （W-G-LASIK） and coneal wavefront aberration guided laser epithelial keratomileusis （W-G- LASEK） on higher order aberrations （HOAs） in patients with myopia. Methods 122 eyes of 61 cases un- derwent W-G-LASIK or W-G-LASEK for myopia, including 27 cases （54 eyes） in W-G-LASIK （group A） and 34 cases （68 eyes） in W-G-LASEK （group B）. An examination of HOAs was performed on each eye preoperatively and 7 d, 1 and 3 months postoperatively. Results The results of total HOAs root mean square （RMS） showed an increase in both the two groups compared with that of preoperative one. The 3rd and 4th high order aberration were dominantly increased. It was lower in group B than in group A in total, 3rd, 4th high order aberration（P 〈 0.05 ）. The vertical coma （ C7 ）, horizontal coma （ C8 ） and spherical aberration （C12） were increased after operation in both of the two groups （P 〈 0. 05 ）. And there was signif- icant difference between the two groups in C7, which was higher in group A （P 〈 0. 05 ）. Conclusion Both W-G-LASIK and W-G-LASEK could increase the HOAs, but the HOAs after W-G-LASEK was lower than that after W-G-LASIK.

关 键 词：准分子激光原位角膜磨镶术 准分子激光角膜上皮瓣下磨镶术 角膜波前像差 

分 类 号：R779.63[医药卫生—眼科]