急性缺血性脑卒中CISS分型与危险因素相关性分析  

Analysis of the relationship between Chinese ischemic stroke subclassification and risk factors of acute cerebral ischemic stroke

作　　者：谭丽艳[1] 宋永斌[1] 焦岩[1] 郑俊[1] 杨俊[1] 徐江涛[1] 

机构地区：[1]兰州军区乌鲁木齐总医院神经内科

出　　处：《中华脑血管病杂志（电子版）》2013年第2期22-29,共8页Chinese Journal of Cerebrovascular Diseases(Electronic Edition)

摘　　要：目的探讨急性缺血性卒中中国缺血性卒中亚型(CISS)分型与不同危险因素的关系。方法回顾性分析连续登记的急性缺血性脑梗死患者,记录其危险因素,并按CISS分型标准将急性缺血性卒中分为5种类型并分析相关因素对其发生风险的影响。结果在纳入标准的212例急性缺血性卒中患者中,大动脉粥样硬化型99例(46.7%)、心源性卒中型35例(16.5%)、穿支动脉疾病45例(21.2%)、其他病因型5例(2.4%)、病因不确定型28例(13.2%)。吸烟者、高血压病、冠心病、心房颤动者在5亚型间比例差异具有统计学意义(P<0.05)。相关和回归分析显示冠心病、心房颤动与心源性卒中亚型有正相关性(β=1.34、2.206,P<0.05),高血压病与穿支动脉疾病亚型有相关性,为正相关性(β=1.074,P<0.05)。结论不同类型缺血性脑卒中与不同的危险因素有关,心房颤动、冠心病是心源性卒中亚型的危险因素,高血压病是穿支动脉疾病亚型的危险因素。Objective To explore the relationships between Chinese ischemic stroke subclassification（CISS）and risk factors of acute cerebral ischemic stroke.Methods The clinical data of patients with acute cerebral infarction（ACI） were analyzed retrospectively.Their diagnoses were established by imaging and other etiological examinations.The subtypes of patients were identified according to CISS criteria,and their major risk factors were investigated and analyzed.Results Our study cohort comprised included 212 patients with acute ischemic stroke.There were 99 patients with large artery atherosclerotic cerebral infarction（LAA）,35 with cardiogenic stroke（CS）,48 with penetrating artery disease（PAD）,5 with stroke of other etiologies（OE）,and 28 with stroke of undetermined etiologies（UE）.There are some statistically significant differences in the proportion of the smokers,hypertension,coronary heart disease and atrial fibrillation among these subtypes.Regression and correlation analysis showed that coronary heart disease and atrial fibrillation were positive correlation with CS（β=1.34、2.206,P〈0.05）,hypertension was positive correlation with PAD（β=1.074,P〈0.05）.Conclusion Different stroke subtypes in etiology could be associated with different risk factors,coronary heart disease and atrial fibrillation were the risk factors for CS,and hypertension was a risk factor for PAD.

关 键 词：急性缺血性脑卒中 CISS分型 危险因素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]