胶囊内镜检查的肠道准备方法探讨  

Assessment of two bowel preparation methods for capsule endoscopy

作　　者：李爱琴[1] 金鹏[1] 唐玉芬[1] 王海红[1] 余东亮[1] 汤珊[1] 盛剑秋[1] 

机构地区：[1]北京军区总医院消化内科,北京100700

出　　处：《胃肠病学和肝病学杂志》2013年第7期677-679,共3页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的探讨改善胶囊内镜观察效果的肠道准备方法。方法拟行胶囊内镜检查的患者91例,随机分为两组,接受不同的肠道准备方法。实验组(n=46):检查前一天20:00吞服两片酚酞片,检查前15 min口服西甲硅油消泡剂30 ml,吞服胶囊内镜后饮用20%甘露醇溶液250 ml+温开水250 ml。对照组(n=45):检查当日凌晨5:00口服50%硫酸镁溶液100 ml+温开水2 000 ml。比较两组患者的不良反应发生率、肠道清洁程度和胶囊内镜的通过时间。结果实验组较对照组不良反应发生率显著降低(0 vs11.1%,P=0.026);实验组肠道清洁状况优于对照组(Z=-2.213,P=0.027);实验组与对照组胶囊内镜通过小肠的时间无明显差异[(265.2±70.2)min vs(323.6±77.8)min,P=0.073]。结论联合应用酚酞片、西甲硅油和甘露醇溶液进行胶囊内镜检查前肠道准备,可达到理想的清肠效果,且患者不良反应较少,值得在临床推广。Objective To investigate the optimal bowel preparation for capsule endoscopy （CE）. Methods 91 patients were recruited for CE and randomly divided into two groups. The experimental group （n = 46） took two phenol- phthalein tablets at 8：00 pm on the day before examination, and drunk 30 ml Simethicone defoamer 15 minutes before examination. After swallowed the capsule, the patients should drank 250 ml mannitol （20%） and 250 ml water. The control group （n = 45 ） drunk 100 ml adlerirka （50%） and 2 000 ml water at 5 am on the examination day. The adverse effects rate, the status of bowel preparation and the transit time of capsule in each group were calculated. Results The adverse effects rate in experimental group was better than that in the control group （0 vs 11.1% ,P = 0. 026）. The status of bowel preparation in the experimental group was better than that in the control group （Z = -2.213 ,P = 0. 027）. The transit time of capsule in each group was similar [ （265.2 ± 70.2） rain vs （323.6 ± 77.8） min,P = 0. 073 ]. Conclusion Combined phenolphthalein tablets, simethicone and mannitol for bowel preparation is suitable before capsule endoscopy examination.

关 键 词：胶囊内镜 肠道准备 小肠 

分 类 号：R574[医药卫生—消化系统]