SWAN检测脑微出血在老年腔隙性脑梗塞病人危险性评估中的应用  

Risk Assessment in Elderly Patients with Lacunar Infarction by Detecting of Cerebral Microbleeds with SWAN

作　　者：李政义[1] 韩鹏熙[1] 李伟[1] 李爱银[1] 

机构地区：[1]山东省千佛山医院影像科,山东济南250014

出　　处：《中国CT和MRI杂志》2013年第4期1-3,共3页Chinese Journal of CT and MRI

基　　金：山东省自然科学基金项目(编号:ZR2010HL019)

摘　　要：目的应用SWAN序列检测CMBs,观察CMBs在腔隙性脑梗塞病人危险性评估中的临床价值。方法本实验共选取79名腔隙性脑梗塞患者,平均年龄69.2岁,参与者在1.5T磁共振均接受常规T2WI以及高分辨SWAN序列两次扫描,记录血管疾病危险性因素:年龄、高血压、高血脂及腔隙性脑梗塞等,所得数据应用统计学方法进行分析。结果高血压、高血脂及腔隙性脑梗塞病人出现CMBs的几率较高。随访观察,在SWAN检查确认有CMBs的组别中较未发现CMBs的组别中,腔隙性脑梗塞严重程度加重,新发CMBs几率较高(25.8%对8.3%),有显著统计学差异。结论在老年腔隙性脑梗塞病人中,CMBs的出现提示小血管病变风险显著增加,再发腔隙性脑梗塞的几率增大。Objective The clinical value of risk assessment in patients with lacunar infarction detection of cerebral microbleeds by SWAN. Materials＇ and methods Senventy nine participants （mean age, 69.2 years） underwent both conventional GRE T2＊-weighted MR imaging and SWAN MR imaging at 1.5T.Vascular risk factors, age, hypertension, high cholesterol and lacunar infarction, was recorded. The data was analyzed by application of statistical methods, Restdts High blood pressure, high cholesterol and lacunar infarction patients had a higher risk of CMBs. Follow-up observation, However, the degree of lacunar infarction in these participants whose microbleeds were depicted on SWAN MR imaging sequence was more severity to those in participants than to those in participants without microbleeds. Moreover, significantly more participants whose microbleeds were demon- strated on SWAN MR imaging developed new CMBs during follow-up compared with participants without CMBs （25.8% versus 8.3%）. Conclusion In elderly patients with lacunar cerebra/infarction, the emergence of CMBs shows increasing risk of small vascular lesions and recurrence of lacunar cerebral infarction.

关 键 词：脑梗塞 脑微出血 老年人 磁共振成像 重度T2*加权成像 

分 类 号：R743.33[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]