微波热凝联合平阳霉素瘤体内注射治疗颌面部血管瘤的临床疗效观察  

Clinical effect of microwave thermosetting joint pingyangmycin injected within the occlusion in treatment of maxillofacial hemangioma

作　　者：王焱[1] 

机构地区：[1]保定市第二中心医院口腔科,河北省保定072750

出　　处：《中国基层医药》2013年第14期2134-2136,共3页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的观察微波热凝联合平阳霉素瘤体内注射治疗颌面部血管瘤的临床疗效及安全性。方法对102例颌面部血管瘤患者的临床资料进行回顾性分析，根据不同时期选择治疗方法的不同分为微波热凝组54例和手术组48例，对两组的临床疗效、治疗时间及美容效果等进行对比分析。结果微波热凝组总有效率为96．30％，手术组总有效率为95．83％，两组差异无统计学意义（x2=0．153，P〉0．05）。手术组治疗时间明显短于微波热凝组[（25．5±3．2）d与（31．6±4．8）d，t=7．625，P〈0．01]，但微波热凝组美容效果满意度明显高于手术组（90．74％与75．00％，X2=4．533，P〈0．05），不良反应发生率也明显低于手术组（5．56％与18．75％，x2=4．262，P〈0．05）。手术组术后发生面神经损伤者3例（6．25％），微波热凝组治疗后无面神经损伤病例。6个月随访中，均未发现复发病例。结论微波热凝联合平阳霉素瘤体内注射治疗颌面部血管瘤临床效果和美容效果满意，不良反应及并发症发生率相对较低，安全、有效，值得临床推广应用。Objective To investigate the clinical effect and safety of microwave thermosetting joint pingyang- mycin injected within the occlusion in treatment of maxillofacial hemangioma. Methods The clinical data of 102 pa- tients with maxillofacial hemangioma were retrospectively analyzed. According to the different period of the different choice of treatment, the patients were divided into microwave thermosetting group and surgery group. The clinical effect,treatment time and hairdressing effect of the two groups were analyzed. Results Total effective rate of micro- wave thermosetting group was 96.30% ,surgery group was 95.83% ,the difference between the two groups had no sta- tistical significance（ X2 = 0. 153 ,P 〉 0.05 ）. The average surgical time of surgery group was obviously shorter than mi- crowave thermosetting group（ t =7. 625 ,P 〈 0.01 ） ,but satisfaction of hairdressing effect in microwave thermosetting group was obviously higher than that of the surgery group（90.74% vs 75.00% ,X2 =4.533 ,P 〈0.05 ） ,the incidence rate of adverse reaction was significantly lower than the surgery group（5.56% vs 18.75%,X2 = 4.262, P 〈 0.05）. The facial nerve injury occurred in 3 patients （ 6.2 5 % ） after operation in the surgery group , microwave thermosetting group had no facial nerve injury after treatment. There was no recurrence after follow-up for 6 months. Conclusion The clinical effect and hairdressing effect of microwave thermosetting joint pingyangmycin injected with-in the occlusion in treatment of maxillofacial hemangioma are satisfied, the incidence rate of adverse reaction and complication is relatively low. It is safe and effective, which is worth expanding in clinical practice.

关 键 词：血管瘤 面部 微波 平阳霉素 

分 类 号：R739.8[医药卫生—肿瘤]