老年人非小细胞肺癌35例手术治疗临床分析  

Clinical analysis of surgical treatment for the aged patients with primary NSCLC： a report of 35 cases

作　　者：冯希武[1] 孙长海[1] 张继洲[1] 谢怀顺[1] 张新伟[1] 陶天晓[1] 刘士学[1] 

机构地区：[1]淮南市第一人民医院心胸外科,安徽省淮南232007

出　　处：《中国基层医药》2013年第14期2139-2141,共3页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的分析老年非小细胞肺癌（NSCLC）患者术后并发症的可能危险因素，探讨围术期的处理措施，以提高手术治疗效果。方法回顾性分析35例老年NSCLC患者的临床资料，对术后并发症的可能危险因素先进行单因素分析，有统计学意义者纳入Logistic回归分析。结果35例患者术后发生各种并发症10例，占28．6％；死亡1例，占2．9％。Logistic回归分析提示慢性支气管炎史、吸烟史、冠心病史、结核病史、第一秒用力呼气容积（FEV1）、肺叶切除、手术方式是术后并发症的独立危险因素（均P〈0．05）。结论正确进行手术前分期，严格掌握手术适应证，选择规范的手术方法，降低手术创伤，加强围术期管理，对老年非小细胞肺癌患者实施外科手术仍能达到令人满意的治疗效果。Objective To investigate the clinical feature of perioperative management of non-small cell lung eancer（NSCLC） in aged patients and improve the efficacy of surgical treatment. Methods The clinical data of 35 aged patients＇ with NSCLC were retrospectively analyzed. The risk factors of postoperative complications were analyzed by single factor analysis, the factors had statistical significance were included in Logistic regression analysis. Results Postoperative complications occurred in 10 cases, accounting for 28.6%, and 1 case died, accounting for 2. 9%. Logistic regression analysis showed that smoking, chronic bronchitis, coronary heart disease ,pulmonary lobecto- my were independent risk factors of postoperative complications. Conclusion Correct staging before operation, strict surgical indication, choose the standard surgical method to reduce surgical trauma, strengthen the perioperative management can still achieve satisfactory therapeutic effect in surgical operation for aged patients with NSCLC.

关 键 词：癌 非小细胞肺 老年人 外科手术 

分 类 号：R734.2[医药卫生—肿瘤]